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Rhesus IGFBP-2 / IGFBP2 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag

Catalog No:CG90083-ACG
NCBI RefSeq:981 bp
Type:Expression-Ready ORF Clones
Gene ID:

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IGFBP-2, also known as IGFBP2, is a insulin-like growth factor-binding protein (IGFBP). IGFBPs prolong the half-life of the IGFs , control bioavailability, activity, and distribution of insulin-like growth factor (IGF) throµgh high-affinity IGFBP/IGF complexes. Six high-affinity IGF-binding proteins (IGFBP-1 to -6) have been identified. The six IGFBPs are structurally related but encoded by distinct genes. IGFBPs have a high affinity for IGFs. Some members of the IGFBP family have been consistently shown to inhibit IGF actions by preventing them from gaining access to the IGF receptors, while others potentiate IGF actions by facilitating the ligand-receptor interaction. IGFBP-2 is overexpressed in many malignancies and is often correlated with an increasingly malignant status of the tumor, pointing to a potential involvement of IGFBP-2 in tumorigenesis. It contains 1 IGFBP N-terminal domain and 1 thyroglobulin type-1 domain. It inhibits IGF-mediated growth and developmental rates.

Rhesus IGFBP-2 / IGFBP2 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag Product information

Molecule NameIGFBP2
RefSeq ORF Size981 bp
cDNA DescriptionRhesus IGFBP-2 / IGFBP2 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag (CG90083-ACG) - available for purchase from ABclonal - allows for easy subcloning of the ORF (pCMV3-C-GFPSpark Vector) to other plasmid vectors.
Restriction site
Sequence Description
PromoterEnhanced CMV mammalian cell promoter
Antibiotic in E.coliKanamycin
Antibiotic in mammalian cellHygromycin
Shipping carrierEach tube contains lyophilized plasmid.
StorageThe lyophilized plasmid can be stored at ambient temperature for three months.

Neucleotide sequence and amino acid sequence

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