Product name | Rabbit anti-Human IL-6 mAb (DET) |
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Catalog No. | RM17652 |
Catagory | Elisa Antibody Kit |
Application | multiplex assay |
Description | Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the membrane-bound IL6R and IL6ST stimulates "classic signaling", whereas the binding of IL6 and soluble IL6R to IL6ST stimulates "trans-signaling". Alternatively, "cluster signaling" occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells (Probable). |
Immunogen | E. coli-derived human IL-6 protein Pro29-Met212 Accession #Q75MH2 |
Purirty | Affinity purification |
Ig Type | Rabbit IgG |
Formulation | Supplied as a 0.2um filtered solution in PBS with 0.1%Braveds MB-1, PH 7.4. |
CrossReactivity | No cross-reactivity in multiplex assay with Recombinant human CNTF、IL-2 、IL-3、G-CSF、 IL-4 、M-CSF、IL-5 、IL-1A、IL-1B 、IL-6RA、IL-6RB、IL-7、IL-8&Recombinant mouse IL-6、IL-2、IL-4、IL-11、 IL-12 |
Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative:0.1%Braveds MB-1 Avoid repeated freeze-thaw cycles. |
Human IL-6 multiplex assay
Recommended Concentration | Sample | |
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Capture | 10ug/106 | Rabbit anti-Human IL-6 mAb (CAP)(Cat. No. RM17650) |
Detection | 0.5-2ug/mL | Rabbit anti-Human IL-6 mAb (DET)(Cat. No. RM17652) |
Standard | 1.4-1000pg/mL | Recombinant IL-6 Protein (Cat. No. RP00201) |
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* For research use only. Not for therapeutic or diagnostic purposes.