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We synthesize peptides up to 200 amino acids in length utilizing our proprietary ligation technology.
Starting from $1.98/amino acid (aa), ABclonal can synthesize peptides with no minimum length requirement. We are proud to deliver peptide synthesis services with success rates higher than 98%.
For peptide synthesis, liquid-phase peptide synthesis (LPPS) is used for shorter peptides to minimize side reactions, while solid-phase peptide synthesis (SPPS) is used for longer peptides to enable rapid separation between the growing peptide and the reaction mixtures. Microwave technology is used to increase the chemical coupling efficiency, improve peptide yields, and enhance success rate.
To ensure that the quality meets your research needs, all peptides include MS and HPLC validation reports will be performed by independent quality assurance parties.
Certificate of analysis includes MS and HPLC analyses. These analyses are followed by independent QA (quality assurance) procedures.
Amidation (C-terminus) or Acetylation (N-terminus)
Acetylation (N-Terminal), HYNIC (N-Terminal), DTPA (N-Terminal), Formylation (N-Terminal), Fatty acid (N-Terminal), Myristic acid (N-Terminal), Palmitoyl (N-Terminal), Benzyloxycarbonylation (CBZ), Amidation (C-Terminal), Succinylation (Suc, N-Terminal), etc.
Special Amino Acid
D-Arg, D-Cys, D-Asp, D-Asn, D-Glu, D-Gln, D-Ser, D-His, D-Thr, D-Trp, D-Leu,D-Ile, D-Met, D-Pro, D-Val ,D-Phe, pGlu, Hyp, D-Lys,D-Tyr, D-Orn, Orn, Abu, Aib, (D)1-Nal, (D)2-Pal, (D)4-Cl-Phe, Nva, Nle, Hse, Hcy, Pen, Mpa,N-Methyl amino acid (Ala, Phe, Leu, Ile, Val, Gly, Met),Other amino acid, Dinitrobenzoylation (Lys), Lys (Me2), Phosphorylation (Tyr, Ser, Thr, single site), Tyr(SO3H2), Ser (octanoic acid), etc.
Fluorescence/Dye labeling
Biotin (N-Terminal, Y/N Ahx), Biotin (Lys in sequence), Biotin (without Lys in sequence), FITC/5-FAM (N-Terminal, Y/N Ahx), Dansyl (N-Terminal, Y/N Ahx), MCA (N-Terminal), p-Nitroanilide (pNA, C-Terminal), AMC (C-Terminal). ABclonal offers a biotin-modified peptide that already has a success rate of nearly 100%.
Multiple Disulfide Bonds
Disulfide bridge bond plays an important role in the stability of protein structure. ABclonal Peptide™ can build up to 4 disulfide bridges between cysteine at specified positions on one peptide.
Multiple Phosphorylations
ABclonal can synthesize serine-, threonine-, and tyrosine-phosphopeptides. For peptides containing one or more of these hydroxy-amino acids, selective phosphorylation can be achieved by orthogonal protection or by Fmoc-protected phosphorylated amino acids. Now we have been able to provide 4 phosphorylated sites modified peptides.
Keyhole Limpet Hemocyanin (KLH), Bovine Serum Albumin(BSA), and Ovalbumin
For generating significant immune responses, peptides are conjugated to more prominent carrier proteins, such as ovalbumin, or BSA or KLH. ABclonal Peptide™ couples the cysteine residue of the peptide to the carrier protein.
PEGylation
PEGylation is the covalent conjugation of macromolecules with polyethylene glycol (PEG), polymers that are nonionic, nontoxic, biocompatible and highly hydrophilic. PEGylation enhances the therapeutic application of macromolecules.
Isotope Labeling
ABclonal can label peptides with stable nonradioactive isotopes such as 2H, 15N, 13C, or both 15N and 13C. Isotope-labeled peptides are mainly used in medical and biological fields at higher prices, to meet the needs of customers, we accept micrograms isotope labeling peptide customization.
Multiple Antigenic Peptide(MAP) systems
Multiple antigenic peptides, consisting of highly localized peptide density and high molecular weight, is one potent way to produce high-titer antipeptide antibodies and synthetic peptide vaccines. This system utilizes lysine to form a backbone to which multiple peptide chains can be attached. ABclonal can form Asymmetric 4 branches and Asymmetric 8 branches.
Quenched Fluorescent Peptide
Abz/ Tyr (3-NO2) and EDANS/DABCYL.
Papers that include peptides synthesized using our services have been published in highly creditable journals such as Cell and other publications.
Certificate of analysis includes MS and HPLC analyses. These analyses are followed by independent QA (quality assurance) procedures.
Amidation (C-terminus) or Acetylation (N-terminus)
Acetylation (N-Terminal), HYNIC (N-Terminal), DTPA (N-Terminal), Formylation (N-Terminal), Fatty acid (N-Terminal), Myristic acid (N-Terminal), Palmitoyl (N-Terminal), Benzyloxycarbonylation (CBZ), Amidation (C-Terminal), Succinylation (Suc, N-Terminal), etc.
Special Amino Acid
D-Arg, D-Cys, D-Asp, D-Asn, D-Glu, D-Gln, D-Ser, D-His, D-Thr, D-Trp, D-Leu,D-Ile, D-Met, D-Pro, D-Val ,D-Phe, pGlu, Hyp, D-Lys,D-Tyr, D-Orn, Orn, Abu, Aib, (D)1-Nal, (D)2-Pal, (D)4-Cl-Phe, Nva, Nle, Hse, Hcy, Pen, Mpa,N-Methyl amino acid (Ala, Phe, Leu, Ile, Val, Gly, Met),Other amino acid, Dinitrobenzoylation (Lys), Lys (Me2), Phosphorylation (Tyr, Ser, Thr, single site), Tyr(SO3H2), Ser (octanoic acid), etc.
Fluorescence/Dye labeling
Biotin (N-Terminal, Y/N Ahx), Biotin (Lys in sequence), Biotin (without Lys in sequence), FITC/5-FAM (N-Terminal, Y/N Ahx), Dansyl (N-Terminal, Y/N Ahx), MCA (N-Terminal), p-Nitroanilide (pNA, C-Terminal), AMC (C-Terminal). ABclonal offers a biotin-modified peptide that already has a success rate of nearly 100%.
Multiple Disulfide Bonds
Disulfide bridge bond plays an important role in the stability of protein structure. ABclonal Peptide™ can build up to 4 disulfide bridges between cysteine at specified positions on one peptide.
Multiple Phosphorylations
ABclonal can synthesize serine-, threonine-, and tyrosine-phosphopeptides. For peptides containing one or more of these hydroxy-amino acids, selective phosphorylation can be achieved by orthogonal protection or by Fmoc-protected phosphorylated amino acids. Now we have been able to provide 4 phosphorylated sites modified peptides.
Keyhole Limpet Hemocyanin (KLH), Bovine Serum Albumin(BSA), and Ovalbumin
For generating significant immune responses, peptides are conjugated to more prominent carrier proteins, such as ovalbumin, or BSA or KLH. ABclonal Peptide™ couples the cysteine residue of the peptide to the carrier protein.
PEGylation
PEGylation is the covalent conjugation of macromolecules with polyethylene glycol (PEG), polymers that are nonionic, nontoxic, biocompatible and highly hydrophilic. PEGylation enhances the therapeutic application of macromolecules.
Isotope Labeling
ABclonal can label peptides with stable nonradioactive isotopes such as 2H, 15N, 13C, or both 15N and 13C. Isotope-labeled peptides are mainly used in medical and biological fields at higher prices, to meet the needs of customers, we accept micrograms isotope labeling peptide customization.
Multiple Antigenic Peptide(MAP) systems
Multiple antigenic peptides, consisting of highly localized peptide density and high molecular weight, is one potent way to produce high-titer antipeptide antibodies and synthetic peptide vaccines. This system utilizes lysine to form a backbone to which multiple peptide chains can be attached. ABclonal can form Asymmetric 4 branches and Asymmetric 8 branches.
Quenched Fluorescent Peptide
Abz/ Tyr (3-NO2) and EDANS/DABCYL.
Papers that include peptides synthesized using our services have been published in highly creditable journals such as Cell and other publications.
