Product Type > Proteins

Recombinant Human ROR1 Protein (RP00438)

Datasheet

Overview

Product name Recombinant Human ROR1 Protein
Catalog No. RP00438
Description Recombinant Human ROR1 Protein is produced by Human Cell expression system. The target protein is expressed with sequence (Gln30-Glu403) of human ROR1 (Accession #Q01973) fused with a 6×His tag at the C-terminus.
Purity > 95% by SDS-PAGE.
Endotoxin < 1 EU/μg of the protein by LAL method.
Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation.
Species Human
This protein belongs a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms.
Synonym ROR1; NTRKR1; dJ537F10.1
Expressed Host HEK293 cells
Tag C-6×His
Swiss-Prot Q01973
Gene ID 4919
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
Reconstitution Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water.

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* For research use only. Not for therapeutic or diagnostic purposes.

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