Product Type > Proteins

Recombinant Human ON/SPARC/BM-40 Protein (RP00446)

Datasheet

Overview

Product name Recombinant Human ON/SPARC/BM-40 Protein
Catalog No. RP00446
Description Recombinant Human ON/SPARC/BM-40 Protein is produced by Human Cell expression system. The target protein is expressed with sequence (Ala18-Ile303) of human ON/SPARC/BM-40 (Accession #P09486) fused with a 6×His tag at the C-terminus.
Bio-Activity Measured by its ability to inhibit the cell growth of Mv1Lu mink lung epithelial cells. The ED50 for this effect is 0.75-3.0 μg/mL.
Purity > 95% by SDS-PAGE.
Endotoxin < 1 EU/μg of the protein by LAL method.
Formulation Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.Contact us for customized product form or formulation.
Species Human
This protein belongs a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion. Three transcript variants encoding different isoforms have been found for this gene.
Synonym SPARC; BM-40; OI17
Expressed Host HEK293 cells
Tag C-6×His
Swiss-Prot P09486
Gene ID 6678
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
Reconstitution Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water.

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* For research use only. Not for therapeutic or diagnostic purposes.

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