Product Type > Proteins

Recombinant Human Lipopolysaccharide-binding protein/LBP Protein (RP00418)

Datasheet

Overview

Product name Recombinant Human Lipopolysaccharide-binding protein/LBP Protein
Catalog No. RP00418
Description Recombinant Human Lipopolysaccharide-binding protein/LBP Protein is produced by Human Cell expression system. The target protein is expressed with sequence (Ala26-Val481) of human LBP/Lipopolysaccharide-binding protein (Accession #P18428) fused with a 6×His tag at the C-terminus.
Purity > 95% by SDS-PAGE.
Endotoxin < 1 EU/μg of the protein by LAL method.
Formulation Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 1 mM EDTA, pH 7.2.Contact us for customized product form or formulation.
Species Human
This protein is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP).
Synonym BPIFD2; LBP
Expressed Host HEK293 cells
Tag C-His
Swiss-Prot P18428
Gene ID 3929
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
Reconstitution Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

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