Product Type > Proteins

Recombinant Human IL-15RA/IL-15 R alpha Protein (RP00394)

Datasheet

Overview

Product name Recombinant Human IL-15RA/IL-15 R alpha Protein
Catalog No. RP00394
Description Recombinant Human IL-15RA/IL-15 R alpha Protein is produced by Human Cell expression system. The target protein is expressed with sequence (Ile31-Thr205) of human IL-15RA/IL-15 R alpha (Accession #Q13261) fused with an Fc tag at the C-terminus.
Purity > 95% by SDS-PAGE.
Endotoxin < 1 EU/μg of the protein by LAL method.
Formulation Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.Contact us for customized product form or formulation.
Species Human
This protein belongs a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.
Synonym IL15RA; CD215
Expressed Host HEK293 cells
Tag C-Fc
Swiss-Prot Q13261
Gene ID 3601
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
Reconstitution Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water.

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