Products > Catalog Proteins > Immune Checkpoint

Recombinant Human CTLA-4/CD152 Protein (RP00343)



Product nameRecombinant Human CTLA-4/CD152 Protein
Catalog No.RP00343
DescriptionRecombinant Human CTLA-4/CD152 Protein is produced by Human Cell expression system. The target protein is expressed with sequence (Lys36-Asp161) of human CTLA-4/CD152 (Accession #P16410) fused with a 6×His tag at the C-terminus.
Purity> 95% by SDS-PAGE.
Endotoxin< 1 EU/μg of the protein by LAL method.
FormulationLyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
This protein is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in This protein have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.
SynonymALPS5; CD; CD152; CELIAC3; CTLA-4; GRD4; GSE; IDDM12
Expressed HostHuman Cells
Tag6×His tag at the C-terminus
Swiss portP16410
Gene ID1493
StorageStore the lyophilized protein at -20°C to -80 °C for long term.|After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
ReconstitutionReconstitute to a concentration of 0.1-0.5 mg/mL in 1X PBS.

Inquire About This Product

Submit your question about RP00343 below and we will get back to you within one business day.

Alternatively, call us at 888.754.5670.

Select size and quantity
Contact us to order