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Recombinant Human CD47/IAP Protein (RP00331)

Datasheet

Overview

Product nameRecombinant Human CD47/IAP Protein
Catalog No.RP00331
DescriptionRecombinant Human CD47/IAP Protein is produced by Human Cell expression system. The target protein is expressed with sequence (Gln19-Pro139) of human CD47/IAP (Accession #Q08722) fused with a 6×His tag at the C-terminus.
Bio-ActivityMeasured by its ability to bind Human SIRPA in functional ELISA. The ED50 for this effect is typically 5-20ng/ml.
Swiss portQ08722
Gene ID961
SpeciesHuman
This protein belongs a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Alternatively spliced transcript variants have been found for this gene.
SynonymIAP; MER6; OA3
Expressed HostHuman cells
Tag6×His tag at the C-terminus
Purity> 95% by SDS-PAGE.
Endotoxin< 1 EU/μg of the protein by LAL method.
FormulationLyophilized from a 0.2 μm filtered solution of 10 mM Tris-Citrate, 150 mM NaCl, pH 8.0.
StorageStore the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
ReconstitutionReconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water.

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