Product Type > Proteins

Recombinant Human CD40 Ligand/CD154/CD40L/TNFSF5 Protein (RP00329)

Datasheet

Overview

Product name Recombinant Human CD40 Ligand/CD154/CD40L/TNFSF5 Protein
Catalog No. RP00329
Description Recombinant Human CD40 Ligand/CD154/CD40L/TNFSF5 Protein is produced by Human Cell expression system. The target protein is expressed with sequence (Met113-Leu261) of human CD40 Ligand/CD154/CD40L/TNFSF5 (Accession #P29965).
Bio-Activity Measured in a cell proliferation assay using B cell-enriched peripheral blood mononuclear cells (PBMC) in the presence of IL-4. The ED50 for this effect is 1-3 μg/mL in the presence of 20 ng/mL of recombinant human IL-4.
Purity > 95% by SDS-PAGE.
Endotoxin < 1 EU/μg of the protein by LAL method.
Formulation Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 200 mM NaCl, 0.1 mM EDTA, pH 7.0.Contact us for customized product form or formulation.
Species Human
This protein is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome.
Synonym CD154; CD40L; HIGM1; IGM; IMD3; T-BAM; TNFSF5; TRAP; gp39; hCD40L; CD40LG
Expressed Host HEK293 cells
Tag No tag
Swiss-Prot P29965
Gene ID 959
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
Reconstitution Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water.

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