Product Type > Proteins

Recombinant Human CCL11/Eotaxin Protein (RP00313)

Datasheet

Overview

Product name Recombinant Human CCL11/Eotaxin Protein
Catalog No. RP00313
Description Recombinant Human CCL11/Eotaxin Protein is produced by E. coli expression system. The target protein is expressed with sequence (Gly24-Pro97) of human CCL11/Eotaxin (Accession #P51671).
Bio-Activity Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with mouse CCR3. The ED50 for this effect is 1-5 ng/mL.
Purity > 95% by SDS-PAGE.
Endotoxin < 1 EU/μg of the protein by LAL method.
Formulation Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH7.4.Contact us for customized product form or formulation.
Species Human
This antimicrobial protein is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections.
Synonym CCL11; SCYA11; eotaxin
Expressed Host E. coli
Tag No tag
Swiss-Prot P51671
Gene ID 6356
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
Reconstitution Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water.

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* For research use only. Not for therapeutic or diagnostic purposes.

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