Product Type > Proteins

Recombinant Human Ubiquitin carboxyl-terminal hydrolase 16 protein (RP10204LQ)

Datasheet

Overview

Product name Recombinant Human Ubiquitin carboxyl-terminal hydrolase 16 protein
Catalog No. RP10204LQ
Purity >90% by SDS-PAGE
Formulation 20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol
Species Human
USP16 is an active deubiquitinating enzyme (DUB) encoded on chromosome 21, trisomy of which causes Down’s syndrome (DS). USP16 is a phosphoprotein, phosphorylation of USP16 controls its cellular localization, but no effect on its DUB activity. USP16 deubiquitinates histone 2A (H2A), through which USP16 might regulate gene expression and cell cycle progression. Increased USP16 protein levels in people with DS might contribute to the development of certain phenotypes of DS.
Synonym USP16; UBP-M; UBPM
Expressed Host sf9 insect cells
Tag His Tag
Swiss-Prot Q9Y5T5
Gene ID 10600
Storage This product is stable at ≤ -70°C for up to 6 months from the date of receipt.
For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature.

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