Product Type > Proteins

Recombinant Human PD-1/PDCD1/CD279 Protein (RP00067)

Datasheet

Overview

Product name Recombinant Human PD-1/PDCD1/CD279 Protein
Catalog No. RP00067
Description Recombinant Human PD-1/PDCD1/CD279 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Leu25-Thr168) of human PD-1 (Accession #NP_005009.2) fused with a 6×His tag at the C-terminus.
Bio-Activity Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human PD-1 at 5 μg/mL (100 μL/well) can bind Recombinant Human PD-L1 with a linear range of 0.5-2 μg/mL.
Purity > 97% by SDS-PAGE.
Endotoxin < 0.1 EU/μg of the protein by LAL method.
Formulation Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation.
Species Human
This protein is a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure.
Synonym PDCD1; CD279; PD-1; PD1; SLEB2; hPD-1; hPD-l; hSLE1; programmed cell death 1; PD-1; CD279; PD1; SLEB2; hPD-1; hPD-l; hSLE1; PD-1/CD279
Expressed Host HEK293 cells
Tag C-His
Swiss-Prot Q15116
Gene ID 5133
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
Reconstitution Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

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Antibodies (3)

Proteins (4)

* For research use only. Not for therapeutic or diagnostic purposes.

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