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Recombinant Human IL-18RAcP Protein (RP01100)

Datasheet

Overview

Product nameRecombinant Human IL-18RAcP Protein
Catalog No.RP01100
DescriptionRecombinant Human IL-18RAcP Protein is produced by Mammalian expression system. The target protein is expressed with sequence (Phe20-Arg356) of human IL-18RAcP (Accession #O95256) fused with a 6×His tag at the C-terminus.
Purity> 95% by SDS-PAGE.
Endotoxin< 1.0 EU/μg of the protein by LAL method.
FormulationLyophilized from a 0.22 μm filtered solution of PBS, pH7.4.Contact us for customized product form or formulation.
SpeciesHuman
This protein is an accessory subunit of the heterodimeric receptor for interleukin 18 (IL18), a proinflammatory cytokine involved in inducing cell-mediated immunity. This protein enhances the IL18-binding activity of the IL18 receptor and plays a role in signaling by IL18. Mutations in this gene are associated with Crohn's disease and inflammatory bowel disease, and susceptibility to celiac disease and leprosy. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
SynonymInterleukin-18 receptor accessory protein (IL18RAP); Accessory protein-like; CD218 antigen-like family member B; CDw218b; IL-1R accessory protein-like; Interleukin-1 receptor 7; Interleukin-18 receptor accessory protein-like; Interleukin-18 receptor beta£
Expressed HostMammalian
TagC-6×His
Swiss-ProO95256
Gene ID8807
StorageStore the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
ReconstitutionReconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water.

* For research use only. Not for therapeutic or diagnostic purposes.

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