Product Type > Proteins

Recombinant Human CD4 Protein (RP00079)

Datasheet

Overview

Product name Recombinant Human CD4 Protein
Catalog No. RP00079
Description Recombinant Human sCD4 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Lys26-Trp390) of human sCD4 (Accession #NP_000607.1) fused with a 6×His tag at the C-terminus.
Bio-Activity Measured by its binding ability in a functional ELISA. Immobilized Human CD4 Protein at 1μg/mL (100 μL/well) can bind CD4 Rabbit mAb with a linear range of 0.006-0.18 ng/mL.
Purity > 97% by SDS-PAGE.
Endotoxin < 0.1 EU/μg of the protein by LAL method.
Formulation Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation.
Species Human
This protein is a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This protein is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system.
Synonym CD4; CD4mut
Expressed Host HEK293 cells
Tag C-His
Swiss-Prot P01730
Gene ID 920
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
Reconstitution Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

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