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Recombinant Human CD47 Protein (RP02027)

Datasheet

Overview

Product nameRecombinant Human CD47 Protein
Catalog No.RP02027
DescriptionRecombinant Mouse B7-H5 Protein is produced by mammalian expression system. The target protein is expressed with sequence (Gln19-Pro139) of human CD47 (Accession #Q08722) fused with a 6xHis tag at the C-terminus.
Bio-ActivityImmobilized Human CD47, His Tag at 0.5ug/mL (100μL/well), dose response curve for Human SIRP alpha, Fc Tag with the EC50 of 96.15ng/mL determined by ELISA.
Purity> 95% by SDS-PAGE.
Endotoxin< 0.1 EU/μg of the protein by LAL method.
FormulationLyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation.
SpeciesHuman
CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene. CD47 belongs to the immunoglobulin superfamily and partners with membrane integrins and also binds the ligands thrombospondin-1 (TSP-1) and signal-regulatory protein alpha (SIRPα).CD-47 acts as a don't eat me signal to macrophages of the immune system which has made it a potential therapeutic target in some cancers.
SynonymIAP; MER6; OA3
Expressed HostMammalian
TagC-His
Swiss-ProQ08722
Gene ID961
StorageStore the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
ReconstitutionReconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water.

* For research use only. Not for therapeutic or diagnostic purposes.

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