Product Type > Proteins

Recombinant Rat B7-2/CD86 Protein (RP00733)

Datasheet

Overview

Product name Recombinant Rat B7-2/CD86 Protein
Catalog No. RP00733
Description Recombinant Rat B7-2/CD86 Protein is produced by Human cells expression system. The target protein is expressed with sequence (Val29-Lys247) of rat B7-2/CD86 (Accession #O35531) fused with a 6×His tag at the C-terminus.
Purity > 95% by SDS-PAGE.
Endotoxin < 1 EU/μg of the protein by LAL method.
Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.Contact us for customized product form or formulation.
Species Rat
T-lymphocyte activation antigen CD86 (B7-2) is a glycosylated protein in the B7 family. B7 family members aretransmembrane cell surface molecules that play important roles in immune activation and the maintenance ofimmune tolerance. It is highly expressed on activated antigen presenting cells. CD86 involved in thecostimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 orCTLA-4. It may play a critical role in the early events of T-cell activation and costimulation of naive T-cells, suchas deciding between immunity and anergy that is made by T-cells within 24 hours after activation. It isexpressed by activated B-lymphocytes and monocytes and promoted by MARCH8 and results in endocytosisand lysosomal degradation.
Synonym T-lymphocyte activation antigen CD86; Activation B7-2 antigen; CD86
Expressed Host HEK293 cells
Tag C-6×His
Swiss-Prot O35531
Gene ID 56822
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
Reconstitution Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water.

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