Product Type > Proteins

Recombinant Mouse IL-22 Protein (RP00490)

Datasheet

Overview

Product name Recombinant Mouse IL-22 Protein
Catalog No. RP00490
Description Recombinant Mouse IL-22 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Leu34-Val179) of mouse IL-22 (Accession #Q9JJY9) fused with an initial Met at the N-terminus.
Purity > 95% by SDS-PAGE.
Endotoxin < 1 EU/μg of the protein by LAL method.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.0.Contact us for customized product form or formulation.
Species Mouse
Interleukin-22 (IL-22) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. MouseIL-22 cDNA encodes a 179 amino acid residue protein with a putative 33 amino acid signal peptide that iscleaved to generate a 147 amino acid mature protein that shares approximately 79% and 22% sequenceidentity with human IL22 and IL10, respectively. IL22 has been shown to activate STAT-1 and STAT-3 in severalhepatoma cell lines and up-regulate the production of acute phase proteins. IL-22 is produced by normalmouse T cells upon Con A activation. Mouse IL-22 expression is also induced in various organs uponlipopolysaccharide injection, suggesting that IL-22 may be involved in inflammatory responses. The functionalIL-22 receptor complex consists of two receptor subunits, IL-22R (previously an orphan receptor named CRF2-9) and IL-10Rβ (previously known as CRF2-4), belonging to the class II cytokine receptor family.
Synonym Interleukin-22; IL-22; IL-10-Related T-Cell-Derived-Inducible Factor; IL-TIF; IL-TIF Alpha; Interleukin-22a; IL-22a; Il22; Il22a; Iltif; Iltifa
Expressed Host E. coli
Tag No tag
Swiss-Prot Q9JJY9
Gene ID 50929
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
Reconstitution Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water.

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Proteins (2)

Antibodies (1)

* For research use only. Not for therapeutic or diagnostic purposes.

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