Product Type > Proteins

Recombinant Mouse FcRn/FCGRT & B2M Heterodimer Protein (RP00694)

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Overview

Product name Recombinant Mouse FcRn/FCGRT & B2M Heterodimer Protein
Catalog No. RP00694
Description Recombinant Mouse FcRn/FCGRT & B2M Heterodimer Protein is produced by Human Cells expression system. The target protein is expressed with sequence (Ser22-Val301(FCRN)&Ile21-Met119(B2M)) of mouse FcRn/FCGRT & B2M Heterodimer (Accession #Q61559&P01887) fused with a 6×His tag at the C-terminus.
Purity > 95% by SDS-PAGE.
Endotoxin < 1 EU/μg of the protein by LAL method.
Formulation Lyophilized from a 0.2 μM filtered solution of PBS, pH 7.4Contact us for customized product form or formulation.
Species Mouse
FcRn complex consist of two subunits: IgG receptor FcRn large subunit p51 ( alpha chain) and Beta-2-microglobulin ( Beta chain). The complexes is similar in structure to MHC class I-like heterodimer. Beta-2-microglobulin involved in the presentation of peptide antigens to the immune system. FcRn binds to the Fcregion of monomeric immunoglobulins gamma, mediates the uptake of IgG from milk, Possible role in transferof immunoglobulin G from mother to fetus. A principal component of antibody transport is the neonatalreceptor for the Fc portion of immunoglobulin, a heterodimer of a MHC-1 alpha-chain homolog ( FcRn ) andbeta-2-microglobulin ( B2M ).
Synonym IgG receptor FcRn; Neonatal Fc receptor; FCRN
Expressed Host HEK293 cells
Tag C-6×His
Swiss-Prot Q61559&P01887
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
Reconstitution Reconstitute to a concentration of 0.1-0.5 mg/mL in 1X PBS.

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