Product Type > Proteins

Recombinant Mouse CX3CL1/Fractalkine Protein (RP00636)

Datasheet

Overview

Product name Recombinant Mouse CX3CL1/Fractalkine Protein
Catalog No. RP00636
Description Recombinant Mouse CX3CL1/Fractalkine Protein is produced by Human cells expression system. The target protein is expressed with sequence (Gln25-Arg337) of mouse CX3CL1/Fractalkine (Accession #O35188) fused with a 6×His tag at the C-terminus.
Purity > 95% by SDS-PAGE.
Endotoxin < 1 EU/μg of the protein by LAL method.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.Contact us for customized product form or formulation.
Species Mouse
Fractalkine(CX3CL1) is a single-pass type I membrane protein and belongs to the intercrine delta family. Itconsists of an extracellular NH2-terminal domain, a mucin-like stalk, a transmembrane α helix, and a shortcytoplasmic tail. CX3CL1 exists in two forms: as a membrane-anchored or as a shed 80-95K glycoprotein.Soluble CX3CL1 is generated by limited proteolysis on the cell surface, and a disintegrin and metallopeptidase10 (ADAM10) and ADAM17/tumor necrosis factor- α -converting enzyme (ADAM17/TACE) participate in thisshedding. It has been suggested that ADAM10 acts in the constitutive shedding, and ADAM17 acts in responseto cell activation. The protein may play a role in regulating leukocyte adhesion and migration processes at theendothelium.
Synonym CX3CL1; Fractalkine; Cx3cl1; Cx3c; Fkn; Scyd1; CX3CL1
Expressed Host HEK293 cells
Tag C-6×His
Swiss-Prot O35188
Gene ID 20312
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
Reconstitution Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water.

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