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Recombinant Human PD-1 Protein (RP00067)

Datasheet

Overview

Product nameRecombinant Human PD-1 Protein
Catalog No.RP00067
DescriptionRecombinant Human PD-1 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Leu25-Thr168) of human PD-1 (Accession #NP_005009.2) fused with a 6×His tag at the C-terminus.
Bio-ActivityMeasured by its binding ability in a functional ELISA. When Recombinant Human PD-1 is immobilized at 1 μg/mL (100 μL/well), the concentration of Recombinant Human B7-H1/PD-L1 Fc Chimera that produces 50% of the optimal binding response is approximately 0.3-1.8 μg/mL.
Purity> 97% by SDS-PAGE.
Endotoxin< 0.1 EU/μg of the protein by LAL method.
FormulationLyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
SpeciesHuman
This protein is a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure.
SynonymCD279; hPD-1; hPD-l; hSLE1; PD-1; PD1; SLEB2
Expressed HostHEK293 cells
Tag6×His tag at the C-terminus
Swiss portQ15116
Gene ID5133
StorageStore the lyophilized protein at -20°C to -80 °C for long term. |After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
ReconstitutionReconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water.

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