Product Type > Proteins

Recombinant Human IL-10RB/IL-10 R beta Protein (RP00583)

Datasheet

Overview

Product name Recombinant Human IL-10RB/IL-10 R beta Protein
Catalog No. RP00583
Description Recombinant Human IL-10RB/IL-10 R beta Protein is produced by Human cells expression system. The target protein is expressed with sequence (Met20-Ser220) of human IL-10RB/IL-10 R beta (Accession #Q08334) fused with an Fc tag at the C-terminus.
Purity > 95% by SDS-PAGE.
Endotoxin < 1 EU/μg of the protein by LAL method.
Formulation Lyophilized from a 0.2 μM filtered solution of PBS, pH 7.4Contact us for customized product form or formulation.
Species Human
Interleukin-10 receptor subunit beta(IL10RB), also known as Cytokine receptor class-II member 4, Cytokinereceptor family 2 member 4, Interleukin-10 receptor subunit 2, belongs to the type II cytokine receptor family.IL10RB is a single- pass type I membrane protein and contains two fibronectin type-III domains. It is anaccessory chain which is essential for the active interleukin 10 receptor complex. Coexpression of IL10RB andIL10RA proteins has been shown to be required for IL10-induced signal transduction. Defects in IL10RB are thecause of inflammatory bowel disease type 25 (IBD25) which is a chronic, relapsing inflammation of thegastrointestinal tract with a complex etiology.
Synonym IL10RB; CDW210B; CRF2-4; CRFB4; D21S58; D21S66; IL-10R2
Expressed Host HEK293 cells
Tag C-Fc
Swiss-Prot Q08334
Gene ID 3588
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
Reconstitution Reconstitute to a concentration of 0.1-0.5 mg/mL in 1X PBS.

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