Product Type > Proteins

Recombinant Human CSF2RA/GMCSFR-alpha/CD116 Protein (RP00563)

Datasheet

Overview

Product name Recombinant Human CSF2RA/GMCSFR-alpha/CD116 Protein
Catalog No. RP00563
Description Recombinant Human GM-CSF R alpha/CSF2RA Protein is produced by Human cells expression system. The target protein is expressed with sequence (Glu23-Gly320) of human GM-CSF R alpha/CSF2RA (Accession #P15509) fused with a 6×His tag at the C-terminus.
Purity > 95% by SDS-PAGE.
Endotoxin < 1 EU/μg of the protein by LAL method.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.Contact us for customized product form or formulation.
Species Human
Granulocyte-Macrophage Colony-Stimulating Factor Receptor Subunit α (CSF2RA) is a single-pass type Imembrane protein which belongs to the type I cytokine receptor family of Type 5 subfamily. The CSF2RA geneis found in the pseudoautosomal region (PAR) of the X and Y chromosomes with some of the isoforms beingmembrane-bound and others being soluble. CSF2RA is a low affinity receptor for granulocyte-macrophagecolony-stimulating factor. CSF2RA transduces a signal that results in the proliferation, differentiation, andfunctional activation of hematopoietic cells. Defects in CSF2RA are the cause of pulmonary surfactantmetabolism dysfunction type 4 (SMDP4).
Synonym CSF2RA; CD116; CDw116; CSF2R; CSF2RAX; CSF2RAY; CSF2RX; CSF2RY; GM-CSF-R-alpha; GMCSFR; GMR; SMDP4
Expressed Host HEK293 cells
Tag C-His
Swiss-Prot P15509
Gene ID 1438
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
Reconstitution Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

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