Product Type > Proteins

Recombinant Human FABP4/A-FABP/ALBP(A29T) Protein (RP00045)

Datasheet

Overview

Product name Recombinant Human FABP4/A-FABP/ALBP(A29T) Protein
Catalog No. RP00045
Description Recombinant Human FABP4/A-FABP/ALBP(A29T) Protein is produced by E. coli expression system. The target protein is expressed with sequence ( Cys2-Ala132 (29Ala/Thr)) of human FABP4 (Ala29Thr) (Accession #NP_001433.1).
Purity > 95% by SDS-PAGE.
Endotoxin < 1.0 EU/μg of the protein by LAL method.
Formulation Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation.
Species Human
Fatty acid-binding protein, adipocyte, also known as Adipocyte-type fatty acid-binding protein. It is a cytoplasm protein which belongs to the calycin superfamily and Fatty-acid binding protein (FABP) family. In familial combined hyperlipidemia (FCHL), FABP4 correlated to body mass index (BMI), waist circumference and homeostasis model assessment (HOMA) index.FABP4 levels were associated with triglyceride-rich lipoproteins. In humans serum FABP4 levels correlate significantly with features of PCOS. It appears to be a determinant of atherogenic dyslipidemia. FABP4 pathway mediates the sebaceous gland hyperplasia in keratinocyte-specific Pten-null mice. FABP4 concentration significantly increased with an increasing of MS features and was strongly correlated with body-mass index, triglycerides, HDL-cholesterol concentrations and blood pressure. FABP4 is a strong plasma marker of metabolic disturbances in HIV-infected patients, and therefore, could serve to guide therapeutic intervention in this group of patients.
Synonym A-FABP; AFABP; ALBP; HEL-S-104; aP2; FABP4; AFABP; ALBP; HEL-S-104; aP2
Expressed Host E. coli
Tag No tag
Swiss-Prot P15090
Gene ID 2167
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
Reconstitution Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

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Antibodies (3)

Proteins (1)

* For research use only. Not for therapeutic or diagnostic purposes.

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