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Recombinant Human CD48/SLAMF2/BCM1 Protein (RP00107)

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Overview

Product nameRecombinant Human CD48/SLAMF2/BCM1 Protein
Catalog No.RP00107
DescriptionRecombinant Human CD48/SLAMF2/BCM1 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Gln27-Ser220) of human CD48/SLAMF2/BCM1 (Accession #NP_001769.2) fused with an Fc, 6×His tag at the C-terminus.
Bio-ActivityMeasured by its binding ability in a functional ELISA. Immobilized rh2B4/Fc Chimera at 5 μg/mL (100 μL/well) can bind Recombinant Human CD48/SLAMF2/BCM1 with a linear range of 0.06-4 μg/mL.
Purity> 97% by SDS-PAGE.
Endotoxin< 0.1 EU/μg of the protein by LAL method.
FormulationLyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
SpeciesHuman
This protein is a member of the CD2 subfamily of immunoglobulin-like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. The encoded protein is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells. The encoded protein does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene.
SynonymBCM1; BLAST; BLAST1; hCD48; mCD48; MEM-102; SLAMF2
Expressed HostHEK293 cells
TagFc, 6×His tag at the C-terminus
Swiss portP09326
Gene ID962
StorageStore the lyophilized protein at -20°C to -80 °C for long term. |After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
ReconstitutionReconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water.

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