Product Type > Proteins

Recombinant Human CCL18/PARC Protein (RP00810)

Datasheet

Overview

Product name Recombinant Human CCL18/PARC Protein
Catalog No. RP00810
Description Recombinant Human CCL18/PARC Protein is produced by E. coli expression system. The target protein is expressed with sequence (Ala21-Ala89) of human CCL18/PARC (Accession #P55774) fused with an initial Met at the N-terminus and a 6×His tag at the N-terminus.
Purity > 95% by SDS-PAGE.
Endotoxin < 1 EU/μg of the protein by LAL method.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.Contact us for customized product form or formulation.
Species Human
C-C Motif Chemokine 18 (CCL18) is secreted protein that belongs to the intercrine beta (chemokine CC) family.CCL18 is expressed at high levels in the lung, lymph nodes, placenta, bone marrow, and dendritic cells. CCL18 isa chemotactic factor that attracts lymphocytes but not monocytes or granulocytes. CCL18 is a novel CCchemokine that is highly homologous to MIP-1 alpha. CCL18 may be involved in B-cell migration into B-cellfollicles in lymph nodes. CCL18 attracts naive T-lymphocytes toward dendritic cells and activated macrophagesin lymph nodes. It has chemotactic activity for naive T-cells, CD4+ and CD8+ T-cells and thus may play a role inboth humoral and cell-mediated immunity responses.
Synonym CCL18; AMAC-1; AMAC1; CKb7; DC-CK1; DCCK1; MIP-4; PARC; SCYA18; PARC; AMAC1; DCCK1; MIP-4; AMAC-1; DC-CK1; SCYA18
Expressed Host E. coli
Tag N-His
Swiss-Prot P55774
Gene ID 6362
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
Reconstitution Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

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