Product Type > Antibodies > Primary Antibodies > Polyclonal Antibodies

TGF beta Receptor I (TGFBR1) Rabbit pAb (A16983)

Publications (12) Datasheet SDS COA

Tested applications: WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra) ELISA MeDIP Nucleotide Array DB FACS CoIP FCM CUT&Tag meRIP Inhibition

Reactivity:Human, Mouse, Rat

ABclonal:Western blot - TGF beta Receptor I (TGFBR1) Rabbit pAb (A16983)

Western blot analysis of various lysates using TGF beta Receptor I (TGFBR1) Rabbit pAb (A16983) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 60s.

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Overview

Product name TGF beta Receptor I (TGFBR1) Rabbit pAb
Catalog No. A16983
Host species Rabbit
Purification method Affinity purification
Isotype IgG

Background

The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.

Immunogen information

Immunogen A synthetic peptide corresponding to a sequence within amino acids 161-179 of human TGF beta Receptor I (TGFBR1) (NP_004603.1).
Sequence EEDPSLDRPFISEGTTLKD
Gene ID 7046
Swiss prot P36897
Synonyms AAT5; ALK5; ESS1; LDS1; MSSE; SKR4; TBRI; ALK-5; LDS1A; LDS2A; TBR-i; TGFR-1; ACVRLK4; tbetaR-I; TGF beta Receptor I (TGFBR1)
Calculated MW 56kDa
Observed MW 56kDa

Applications

Reactivity Human, Mouse, Rat
Tested applications WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra) ELISA MeDIP Nucleotide Array DB FACS CoIP FCM CUT&Tag meRIP Inhibition
Recommended dilution
  • WB 1:500 - 1:1000
Storage buffer Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Application key Western blotting    
Positive samples PC-3, Mouse lung
Cellular location Cell junction, Cell membrane, Single-pass type I membrane protein, tight junction
Customer validation

WB (Rattus norvegicus, Homo sapiens, Mus musculus)

IF (Mus musculus, Homo sapiens)

Documents

Certificate of Compliance

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Lot number

Research Area

TGF beta Receptor I (TGFBR1) Rabbit pAb images

ABclonal:Western blot - TGF beta Receptor I (TGFBR1) Rabbit pAb (A16983)}

Western blot - TGF beta Receptor I (TGFBR1) Rabbit pAb (A16983)

Western blot analysis of various lysates using TGF beta Receptor I (TGFBR1) Rabbit pAb (A16983) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 60s.

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Related Targets

Based on existing publications, the following genes are closely related to research on TGFBR1. (Numbers indicate number of published articles where both targets appear.)

1/

Related Research Area

Based on existing publications, the following research topics are related to TGFBR1. (Distance between topics and target gene indicate popularity.) TGFBR1

* Data provided by citexs.com, for reference only.

Publishing research using A16983? Please let us know so that we can cite the reference in this datasheet.

Antibodies (2)

Proteins (1)

ELISA Kits (1)

Secondary Antibodies (23)

* For research use only. Not for therapeutic or diagnostic purposes.

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