Product Type > Antibodies > Primary Antibodies > Phospho-specific Antibodies

Phospho-TrkB-Y515 Rabbit pAb (AP0422)

Datasheet SDS

Tested applications: WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra) ELISA MeDIP Nucleotide Array DB FACS CoIP FCM CUT&Tag meRIP Inhibition

Reactivity:Human, Mouse, Rat

ABclonal:Immunofluorescence - Phospho-TrkB-Y515 Rabbit pAb (AP0422)

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Overview

Product name Phospho-TrkB-Y515 Rabbit pAb
Catalog No. AP0422
Host species Rabbit
Purification method Affinity purification
Isotype IgG

Background

This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.

Immunogen information

Immunogen A phospho specific peptide corresponding to residues surrounding Y515 of human TrkB
Sequence Email for sequence
Gene ID 4915
Swiss prot Q16620
Synonyms OBHD; TRKB; DEE58; trk-B; EIEE58; GP145-TrkB; Phospho-TrkB-Y515
Calculated MW 92kDa
Observed MW

Applications

Reactivity Human, Mouse, Rat
Tested applications WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra) ELISA MeDIP Nucleotide Array DB FACS CoIP FCM CUT&Tag meRIP Inhibition
Recommended dilution
Storage buffer Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application key
Positive samples
Cellular location Cell membrane, Endosome membrane, Single-pass type I membrane protein

Research Area

Phospho-TrkB-Y515 Rabbit pAb images

ABclonal:Immunofluorescence - Phospho-TrkB-Y515 Rabbit pAb (AP0422)}

Immunofluorescence - Phospho-TrkB-Y515 Rabbit pAb (AP0422)

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Related Targets

Based on existing publications, the following genes are closely related to research on NTRK2. (Numbers indicate number of published articles where both targets appear.)

1/

Related Research Area

Based on existing publications, the following research topics are related to NTRK2. (Distance between topics and target gene indicate popularity.) NTRK2

* Data provided by citexs.com, for reference only.

Publishing research using AP0422? Please let us know so that we can cite the reference in this datasheet.

Antibodies (6)

Proteins (1)

Secondary Antibodies (23)

* For research use only. Not for therapeutic or diagnostic purposes.

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