Product Type > Antibodies > Primary Antibodies > Phospho-specific Antibodies

Phospho-TAK1-T187 Rabbit pAb (AP0811)

Datasheet

Tested applications: WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra) ELISA MeDIP Nucleotide Array DB FACS CoIP FCM CUT&Tag meRIP Inhibition

Reactivity:Human, Mouse

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Overview

Product name Phospho-TAK1-T187 Rabbit pAb
Catalog No. AP0811
Host species Rabbit
Purification method Affinity purification
Isotype IgG

Background

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

Immunogen information

Immunogen A synthetic phosphorylated peptide around T187 of human TAK1 (NP_003179.1).
Sequence HMTNN
Gene ID 6885
Swiss prot O43318
Synonyms CSCF; FMD2; TAK1; MEKK7; TGF1a; Phospho-TAK1-T187
Calculated MW 67kDa
Observed MW Refer to figures

Applications

Reactivity Human, Mouse
Tested applications WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra) ELISA MeDIP Nucleotide Array DB FACS CoIP FCM CUT&Tag meRIP Inhibition
Recommended dilution
  • WB 1:500 - 1:2000
Storage buffer Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Application key Western blotting    
Positive samples
Cellular location Cell membrane, Cytoplasm, Cytoplasmic side, Peripheral membrane protein

Research Area

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Related Targets

Based on existing publications, the following genes are closely related to research on MAP3K7. (Numbers indicate number of published articles where both targets appear.)

1/

Related Research Area

Based on existing publications, the following research topics are related to MAP3K7. (Distance between topics and target gene indicate popularity.) MAP3K7

* Data provided by citexs.com, for reference only.

Publishing research using AP0811? Please let us know so that we can cite the reference in this datasheet.

Antibodies (5)

Secondary Antibodies (23)

* For research use only. Not for therapeutic or diagnostic purposes.

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