Product Type > Antibodies > Primary Antibodies > Phospho-specific Antibodies

Phospho-Bim-S69 Rabbit pAb (AP0313)

Datasheet SDS

Tested applications: WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra) ELISA MeDIP Nucleotide Array DB FACS CoIP FCM CUT&Tag meRIP Inhibition

Reactivity:Human, Mouse, Rat

ABclonal:Immunohistochemistry - Phospho-Bim-S69 Rabbit pAb (AP0313)

ABclonal:Immunofluorescence - Phospho-Bim-S69 Rabbit pAb (AP0313)

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Overview

Product name Phospho-Bim-S69 Rabbit pAb
Catalog No. AP0313
Host species Rabbit
Purification method Affinity purification
Isotype IgG

Background

The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified.

Immunogen information

Immunogen A phospho specific peptide corresponding to residues surrounding S69 of human BCL2L11
Sequence Email for sequence
Gene ID 10018
Swiss prot O43521
Synonyms BAM; BIM; BOD; Phospho-Bim-S69
Calculated MW 22kDa
Observed MW

Applications

Reactivity Human, Mouse, Rat
Tested applications WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra) ELISA MeDIP Nucleotide Array DB FACS CoIP FCM CUT&Tag meRIP Inhibition
Recommended dilution
  • IF/ICC 1:100 - 1:200
Storage buffer Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application key Immunofluorescence    
Positive samples
Cellular location Endomembrane system, Mitochondrion, Peripheral membrane protein

Research Area

Phospho-Bim-S69 Rabbit pAb images

ABclonal:Immunohistochemistry - Phospho-Bim-S69 Rabbit pAb (AP0313)}

Immunohistochemistry - Phospho-Bim-S69 Rabbit pAb (AP0313)

ABclonal:Immunofluorescence - Phospho-Bim-S69 Rabbit pAb (AP0313)}

Immunofluorescence - Phospho-Bim-S69 Rabbit pAb (AP0313)

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Related Targets

Based on existing publications, the following genes are closely related to research on BCL2L11. (Numbers indicate number of published articles where both targets appear.)

1/

Related Research Area

Based on existing publications, the following research topics are related to BCL2L11. (Distance between topics and target gene indicate popularity.) BCL2L11

* Data provided by citexs.com, for reference only.

Publishing research using AP0313? Please let us know so that we can cite the reference in this datasheet.

Antibodies (4)

Secondary Antibodies (23)

* For research use only. Not for therapeutic or diagnostic purposes.

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