Product Type > Antibodies > Primary Antibodies > Polyclonal Antibodies

N-Cadherin Rabbit pAb (A0433)

Review (1) Publications (24) Datasheet SDS COA

Tested applications: WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra) ELISA MeDIP Nucleotide Array DB FACS CoIP FCM CUT&Tag meRIP Inhibition

Reactivity:Mouse, Rat

ABclonal:Western blot - N-Cadherin Rabbit pAb (A0433)

Western blot analysis of Mouse heart, using N-Cadherin antibody (A0433) at 1:700 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 30s.

ABclonal:Immunohistochemistry - N-Cadherin Rabbit pAb (A0433)

Immunohistochemistry analysis of paraffin-embedded mouse heart using N-Cadherin Rabbit pAb (A0433) at dilution of 1:50 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.

Immunohistochemistry analysis of paraffin-embedded rat heart using N-Cadherin Rabbit pAb (A0433) at dilution of 1:50 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.

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Overview

Product name	N-Cadherin Rabbit pAb
Catalog No.	A0433
Host species	Rabbit
Purification method	Affinity purification
Isotype	IgG

Background

This gene encodes a classical cadherin and member of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein is proteolytically processed to generate a calcium-dependent cell adhesion molecule and glycoprotein. This protein plays a role in the establishment of left-right asymmetry, development of the nervous system and the formation of cartilage and bone.

Immunogen information

Immunogen	A synthetic peptide corresponding to a sequence within amino acids 807-906 of human N-Cadherin (NP_001783.2).
Sequence	RRMDERPIHAEPQYPVRSAAPHPGDIGDFINEGLKAADNDPTAPPYDSLLVFDYEGSGSTAGSLSSLNSSSSGGEQDYDYLNDWGPRFKKLADMYGGGDD
Gene ID	1000
Swiss prot	P19022
Synonyms	CDHN; NCAD; ACOGS; ADHD8; CD325; ARVD14; CDw325; N-Cadherin
Calculated MW	100kDa
Observed MW	140kDa

Applications

Reactivity	Mouse, Rat
Tested applications	WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra) ELISA MeDIP Nucleotide Array DB FACS CoIP FCM CUT&Tag meRIP Inhibition
Recommended dilution	WB 1:500 - 1:1000 IHC-P 1:50 - 1:200
Storage buffer	Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Application key	Western blotting Immunohistochemistry
Positive samples	Mouse heart
Cellular location	Cell membrane, Single-pass type I membrane protein
Customer validation	WB (U87MG, Homo sapiens, Mus musculus) ICC (Homo sapiens) IHC (Homo sapiens) IHC (Mus musculus) IHC (Homo sapiens)

Documents

Certificate of Compliance

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Research Area

N-Cadherin Rabbit pAb images

Western blot - N-Cadherin Rabbit pAb (A0433)

Immunohistochemistry - N-Cadherin Rabbit pAb (A0433)

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Related Targets

Based on existing publications, the following genes are closely related to research on CDH2. (Numbers indicate number of published articles where both targets appear.)

◀1/▶

Related Research Area

Based on existing publications, the following research topics are related to CDH2. (Distance between topics and target gene indicate popularity.) CDH2

* Data provided by citexs.com, for reference only.

References for N-Cadherin Rabbit pAb (A0433)

Product:

N-Cadherin Rabbit pAb

Journal:

Journal Of The Neurological Sciences

Application:

WB, ICC

IF:

3.181

Species:

Homo sapiens

PMID:

26723972

Title:

Periostin activates pathways involved in epithelial-mesenchymal transition in adamantinomatous craniopharyngioma

References for N-Cadherin Rabbit pAb (A0433)

Product:

N-Cadherin Rabbit pAb

Journal:

CELL DEATH & DISEASE

Application:

WB, IHC

IF:

8.469

Species:

Homo sapiens

PMID:

29695839

Title:

Repression of let-7a cluster prevents adhesion of colorectal cancer cells by enforcing a mesenchymal phenotype in presence of liver inflammation

References for N-Cadherin Rabbit pAb (A0433)

Product:

N-Cadherin Rabbit pAb

Journal:

International journal of oncology

Application:

IF:

5.65

Species:

Homo sapiens

PMID:

31115511

Title:

Leptin stimulates the epithelial‑mesenchymal transition and pro‑angiogenic capability of cholangiocarcinoma cells through the miR‑122/PKM2 axis.

References for N-Cadherin Rabbit pAb (A0433)

Product:

N-Cadherin Rabbit pAb

Journal:

Molecular cancer

Application:

IF:

27.401

Species:

Mus musculus

PMID:

31122259

Title:

miR-301a promotes lung tumorigenesis by suppressing Runx3.

References for N-Cadherin Rabbit pAb (A0433)

Product:

N-Cadherin Rabbit pAb

Journal:

Journal of Cellular Biochemistry

Application:

IF:

4.429

Species:

Homo sapiens

PMID:

31696971

Title:

SNHG16 as the miRNA let-7b-5p sponge facilitates the G2/M and epithelial-mesenchymal transition by regulating CDC25B and HMGA2 expression in hepatocellular carcinoma

References for N-Cadherin Rabbit pAb (A0433)

Product:

N-Cadherin Rabbit pAb

Journal:

Prostate

Application:

IF:

4.1

Species:

Homo sapiens

PMID:

34553788

Title:

Upregulated bone morphogenetic protein 5 enhances proliferation and epithelial-mesenchymal transition process in benign prostatic hyperplasia via BMP/Smad signaling pathway

References for N-Cadherin Rabbit pAb (A0433)

Product:

N-Cadherin Rabbit pAb

Journal:

FEBS Open Bio

Application:

IHC

IF:

2.693

Species:

Mus musculus

PMID:

30524946

Title:

Interleukin-18 expression in oral squamous cell carcinoma: its role in tumor cell migration and invasion, and growth of tumor cell xenografts.

References for N-Cadherin Rabbit pAb (A0433)

Product:

N-Cadherin Rabbit pAb

Journal:

Biochem Biophys Res Commun

Application:

IF:

3.575

Species:

Homo sapiens

PMID:

32828296

Title:

MiR-135b promotes HCC tumorigenesis through a positive-feedback loop

References for N-Cadherin Rabbit pAb (A0433)

Product:

N-Cadherin Rabbit pAb

Journal:

Cancer Gene Ther

Application:

IF:

5.987

Species:

Homo sapiens

PMID:

32855541

Title:

circSFMBT1 promotes pancreatic cancer growth and metastasis via targeting miR-330-5p/PAK1 axis

References for N-Cadherin Rabbit pAb (A0433)

Product:

N-Cadherin Rabbit pAb

Journal:

Front Pharmacol

Application:

IF:

5.81

Species:

Homo sapiens

PMID:

33679411

Title:

Isorhamnetin Inhibits Human Gallbladder Cancer Cell Proliferation and Metastasis via PI3K/AKT Signaling Pathway Inactivation.

References for N-Cadherin Rabbit pAb (A0433)

Product:

N-Cadherin Rabbit pAb

Journal:

Biochem Biophys Res Commun

Application:

IF:

3.575

Species:

Homo sapiens

PMID:

33631676

Title:

FLOT2 upregulation promotes growth and invasion by interacting and stabilizing EphA2 in gliomas

References for N-Cadherin Rabbit pAb (A0433)

Product:

N-Cadherin Rabbit pAb

Journal:

Transl Lung Cancer Res

Application:

IF:

6.49

Species:

Homo sapiens

PMID:

33889522

Title:

circFBXW7 attenuates malignant progression in lung adenocarcinoma by sponging miR-942-5p

References for N-Cadherin Rabbit pAb (A0433)

Product:

N-Cadherin Rabbit pAb

Journal:

Int Immunopharmacol

Application:

IHC

IF:

4.93

Species:

Mus musculus

PMID:

34678694

Title:

Bixin protects mice against bronchial asthma though modulating PI3K/Akt pathway

References for N-Cadherin Rabbit pAb (A0433)

Product:

N-Cadherin Rabbit pAb

Journal:

Technol Cancer Res Treat

Application:

IF:

3.399

Species:

Homo sapiens

PMID:

34657484

Title:

Influence of Autophagy Inhibition on Lung Adenocarcinoma Cell Migration and Invasion Ability, and Efficacy of Gefitinib

References for N-Cadherin Rabbit pAb (A0433)

Product:

N-Cadherin Rabbit pAb

Journal:

BMC Cancer

Application:

IF:

4.43

Species:

Homo sapiens

PMID:

34774019

Title:

MicroRNA-1915-3p inhibits cell migration and invasion by targeting SET in non-small-cell lung cancer

References for N-Cadherin Rabbit pAb (A0433)

Product:

N-Cadherin Rabbit pAb

Journal:

Cell Death Discov

Application:

IF:

5.241

Species:

Homo sapiens,Mus musculus

PMID:

34759267

Title:

Small nucleolar RNA 42 promotes the growth of hepatocellular carcinoma through the p53 signaling pathway

References for N-Cadherin Rabbit pAb (A0433)

Product:

N-Cadherin Rabbit pAb

Journal:

Pharmacological research

Application:

IF:

10.33

Species:

Mus musculus

PMID:

36116708

Title:

Anti-metastatic effects of 1, 2, 3, 4, 6-Penta-O-galloyl-β-D-glucose in colorectal cancer: regulation of cathepsin B-mediated extracellular matrix dynamics and epithelial …

References for N-Cadherin Rabbit pAb (A0433)

Product:

N-Cadherin Rabbit pAb

Journal:

Cell death discovery

Application:

IF:

7.1

Species:

Homo sapiens

PMID:

35927229

Title:

Up-regulation of SLC27A2 suppresses the proliferation and invasion of renal cancer by down-regulating CDK3-mediated EMT - PMC

References for N-Cadherin Rabbit pAb (A0433)

Product:

N-Cadherin Rabbit pAb

Journal:

The Journal of investigative dermatology

Application:

IF:

7.59

Species:

Homo sapiens

PMID:

36521556

Title:

FGF4 promotes skin wound repair through p38 MAPK and GSK3β-mediated stabilization of Slug

References for N-Cadherin Rabbit pAb (A0433)

Product:

N-Cadherin Rabbit pAb

Journal:

International journal of medical sciences

Application:

IF:

3.64

Species:

Homo sapiens

PMID:

36619219

Title:

TRPM2 facilitates tumor progression of clear cell renal cell carcinoma by relieving Endoplasmic Reticulum Stress - PMC

References for N-Cadherin Rabbit pAb (A0433)

Product:

N-Cadherin Rabbit pAb

Journal:

Biochimica et biophysica acta. Molecular basis of disease

Application:

IF:

6.63

Species:

Homo sapiens

PMID:

36773462

Title:

A prospective diagnostic and prognostic biomarker for hepatocellular carcinoma that functions in glucose metabolism regulation: Solute carrier family 37 member 3

References for N-Cadherin Rabbit pAb (A0433)

Product:

N-Cadherin Rabbit pAb

Journal:

Oncogene

Application:

IF:

8.75

Species:

Homo sapiens

PMID:

34799661

Title:

Inner nuclear membrane protein TMEM201 promotes breast cancer metastasis by positive regulating TGFβ signaling

References for N-Cadherin Rabbit pAb (A0433)

Product:

N-Cadherin Rabbit pAb

Journal:

International journal of oncology

Application:

WB, IHC

IF:

5.88

Species:

Homo sapiens

PMID:

36929198

Title:

Cyclovirobuxine D inhibits growth and progression of non‑small cell lung cancer cells by suppressing the KIF11‑CDC25C‑CDK1‑CyclinB1 G2/M phase transition …

References for N-Cadherin Rabbit pAb (A0433)

Product:

N-Cadherin Rabbit pAb

Journal:

Cell death & disease

Application:

IF:

Species:

Homo sapiens

PMID:

37311754

Title: