Products > Catalog Antibodies > Polyclonal Antibodies

NBR1 Rabbit pAb (A3949)

Publication (1) Datasheet

Tested applications:WBIHCICCIFIPChIPChIP-seqRIPFCELISAMeDIPNucleotide ArrayDBFACSCoIPReactivity:Mouse, Rat

ABclonal:Immunofluorescence - NBR1 Rabbit pAb (A3949)

Immunofluorescence analysis of NIH/3T3 cells using NBR1 Rabbit pAb (A3949) at dilution of 1:50 (40x lens). Blue: DAPI for nuclear staining.

ABclonal:Immunofluorescence - NBR1 Rabbit pAb (A3949)

Immunofluorescence analysis of PC-12 cells using NBR1 Rabbit pAb (A3949) at dilution of 1:50 (40x lens). Blue: DAPI for nuclear staining.

Overview

Product nameNBR1 Rabbit pAb
Catalog No.A3949
Host speciesRabbit
Purification methodAffinity purification
IsotypeIgG
The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants.
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human NBR1 (NP_005890.2).
SequenceMEPQVTLNVTFKNEIQSFLVSDPENTTWADIEAMVKVSFDLNTIQIKYLDEENEEVSINSQGEYEEALKMAVKQGNQLQMQVHEGHHVVDEAPPPVVGAKRLAARAGKKPLAHYSSLVRVLGSDMKTPEDPAVQSFPLVPCDTDQPQDKPPDWFTSYLETFREQVVNETVEKLEQKLHEKLVLQNPSLGSCPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVRYQCSLCPSYNICEDCEAGPYGHDTNHVLLKLRRPVVGSSEPFCHSKYSTPRL
Gene ID4077
Swiss protQ14596
SynonymsNBR1; 1A1-3B; IAI3B; M17S2; MIG19
Calculated MW103kDa/107kDa
Observed MW120KDa
ReactivityMouse, Rat
Tested applicationsWBIHCICCIFIPChIPChIP-seqRIPFCELISAMeDIPNucleotide ArrayDBFACSCoIP
Recommended dilution
  • IF 1:50 - 1:100
Storage bufferStore at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application keyImmunofluorescence    
Positive samples
Cellular locationCytoplasm, Cytoplasmic vesicle, Lysosome, M line, autophagosome, myofibril, sarcomere
Customer validation

WB(Mus musculus)

IHC(Mus musculus)

ABclonal:Immunofluorescence - NBR1 Rabbit pAb (A3949)}

Immunofluorescence - NBR1 Rabbit pAb (A3949)

Immunofluorescence analysis of NIH/3T3 cells using NBR1 Rabbit pAb (A3949) at dilution of 1:50 (40x lens). Blue: DAPI for nuclear staining.
ABclonal:Immunofluorescence - NBR1 Rabbit pAb (A3949)}

Immunofluorescence - NBR1 Rabbit pAb (A3949)

Immunofluorescence analysis of PC-12 cells using NBR1 Rabbit pAb (A3949) at dilution of 1:50 (40x lens). Blue: DAPI for nuclear staining.

Inquire About This Product

Submit your question about A3949 below and we will get back to you within one business day.

Alternatively, call us at 888.754.5670.

Publishing research using A3949? Please let us know so that we can cite the reference in this datasheet.

* For research use only. Not for therapeutic or diagnostic purposes.

Select size and quantity
Contact us to order