Products > Catalog Antibodies > Polyclonal Antibodies

IκBα Rabbit pAb (A1187)

Reviews (6)Publications (43) Datasheet

Tested applications:WBIHCICCIFIPChIPChIP-seqRIPFCELISAMeDIPNucleotide ArrayDBFACSCoIPReactivity:Human, Mouse, Rat

Review
ABclonal: review for IκBα Rabbit pAb(A1187)
Review
ABclonal: review for IκBα Rabbit pAb(A1187)
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ABclonal: review for IκBα Rabbit pAb(A1187)
Review
ABclonal: review for IκBα Rabbit pAb(A1187)
Review
ABclonal: review for IκBα Rabbit pAb(A1187)
Review
ABclonal: review for IκBα Rabbit pAb(A1187)

Overview

Product nameIκBα Rabbit pAb
Catalog No.A1187
Host speciesRabbit
Purification methodAffinity purification
IsotypeIgG
This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.
ImmunogenA synthetic peptide corresponding to a sequence within amino acids 200-300 of human IκBα (NP_065390.1).
SequenceELLVSLGADVNAQEPCNGRTALHLAVDLQNPDLVSLLLKCGADVNRVTYQGYSPYQLTWGRPSTRIQQQLGQLTLENLQMLPESEDEESYDTESEFTEFTE
Gene ID4792
Swiss protP25963
SynonymsIKBA; MAD-3; NFKBI; IKB alpha; NFKBIA; EDAID2
Calculated MW35kDa
Observed MW39KDa
ReactivityHuman, Mouse, Rat
Tested applicationsWBIHCICCIFIPChIPChIP-seqRIPFCELISAMeDIPNucleotide ArrayDBFACSCoIP
Recommended dilution
  • WB 1:500 - 1:2000
Storage bufferStore at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application keyWestern blotting    
Positive samplesDU145, MCF7, HeLa
Cellular locationCytoplasm, Nucleus
Customer validation

(Mouse embryonal fibroblast cell, Human glioma, Hela, Mouse splenocytes, HepG2)

WB(Homo sapiens, Mus musculus, Gallus gallus, Rattus norvegicus, Schisandra chinensis, Melodinus cochinchinensis)

IF(Homo sapiens)

IF(Mus musculus)

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Catalog Antibodies (13)

ELISA Kits (1)

Catalog Proteins (1)

Secondary Antibodies (10)

* For research use only. Not for therapeutic or diagnostic purposes.

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