Product Type > Antibodies > Primary Antibodies > Polyclonal Antibodies

DVL2 Rabbit pAb (A14726)

Datasheet SDS

Tested applications:WBIHCIF/ICCIPChIPChIP-seqRIPFCFC(Intra)ELISAMeDIPNucleotide ArrayDBFACSCoIPReactivity:Human

ABclonal:Immunofluorescence - DVL2 Rabbit pAb (A14726)

Immunofluorescence analysis of U2OS cells using DVL2 antibody (A14726) at dilution of 1:100. Blue: DAPI for nuclear staining.

Overview

Product nameDVL2 Rabbit pAb
Catalog No.A14726
Host speciesRabbit
Purification methodAffinity purification
IsotypeIgG

Background

This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans.

Immunogen information

ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human DVL2 (NP_004413.1).
SequenceMAGSSTGGGGVGETKVIYHLDEEETPYLVKIPVPAERITLGDFKSVLQRPAGAKYFFKSMDQDFGVVKEEISDDNARLPCFNGRVVSWLVSSDNPQPEMAPPVHEPRAELAPPAPPLPPLPPERTSGIGDSRPPSFHPNVSSSHENLEPETETESVVSLRRERPRRRDSSEHGAGGHRTGGPSRLERHLAGYESSSTLMTSELESTSLGDSDEEDTMSRFSSSTEQSSASRLLKRHRRRR
Gene ID1856
Swiss protO14641
SynonymsDVL2
Calculated MW78kDa
Observed MW

Applications

ReactivityHuman
Tested applicationsWBIHCIF/ICCIPChIPChIP-seqRIPFCFC(Intra)ELISAMeDIPNucleotide ArrayDBFACSCoIP
Recommended dilution
  • IF/ICC 1:50 - 1:200
Storage bufferStore at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. May contain BSA. If BSA-free batch required, please contact us.
Application key
Positive samples
Cellular locationCell membrane, Cytoplasm, Cytoplasmic side, Cytoplasmic vesicle, Peripheral membrane protein, cytosol

Research Area

DVL2 Rabbit pAb images

ABclonal:Immunofluorescence - DVL2 Rabbit pAb (A14726)}

Immunofluorescence - DVL2 Rabbit pAb (A14726)

Immunofluorescence analysis of U2OS cells using DVL2 antibody (A14726) at dilution of 1:100. Blue: DAPI for nuclear staining.

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Related Targets

Based on existing publications, the following genes are closely related to research on DVL2. (Numbers indicate number of published articles where both targets appear.)

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Related Research Area

Based on existing publications, the following research topics are related to DVL2. (Distance between topics and target gene indicate popularity.) DVL2

* Data provided by citexs.com, for reference only.

Publishing research using A14726? Please let us know so that we can cite the reference in this datasheet.

* For research use only. Not for therapeutic or diagnostic purposes.

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