Product Type > Antibodies > Primary Antibodies > Polyclonal Antibodies

BMPR1B Rabbit pAb (A17295)

Datasheet COA

Tested applications: WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra) ELISA MeDIP Nucleotide Array DB FACS CoIP FCM CUT&Tag meRIP Inhibition

Reactivity:Human, Rat

ABclonal:Immunohistochemistry - BMPR1B Rabbit pAb (A17295)

Immunohistochemistry analysis of BMPR1B in paraffin-embedded human mammary cancer using BMPR1B Rabbit pAb (A17295) at dilution of 1:200 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.

ABclonal:Immunohistochemistry - BMPR1B Rabbit pAb (A17295)

Immunohistochemistry analysis of BMPR1B in paraffin-embedded human colon carcinoma using BMPR1B Rabbit pAb (A17295) at dilution of 1:200 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.

ABclonal:Immunohistochemistry - BMPR1B Rabbit pAb (A17295)

Immunohistochemistry analysis of BMPR1B in paraffin-embedded rat ovary using BMPR1B Rabbit pAb (A17295) at dilution of 1:200 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.

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Overview

Product name BMPR1B Rabbit pAb
Catalog No. A17295
Host species Rabbit
Purification method Affinity purification
Isotype IgG

Background

This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene.

Immunogen information

Immunogen A synthetic peptide corresponding to a sequence within amino acids 1-126 of human BMPR1B (NP_001194.1).
Sequence MLLRSAGKLNVGTKKEDGESTAPTPRPKVLRCKCHHHCPEDSVNNICSTDGYCFTMIEEDDSGLPVVTSGCLGLEGSDFQCRDTPIPHQRRSIECCTERNECNKDLHPTLPPLKNRDFVDGPIHHR
Gene ID 658
Swiss prot O00238
Synonyms ALK6; AMD3; AMDD; BDA2; ALK-6; BDA1D; CDw293; BMPR1B
Calculated MW 57kDa
Observed MW Refer to figures

Applications

Reactivity Human, Rat
Tested applications WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra) ELISA MeDIP Nucleotide Array DB FACS CoIP FCM CUT&Tag meRIP Inhibition
Recommended dilution
  • IHC-P 1:50 - 1:200
Storage buffer Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Application key Immunohistochemistry    
Positive samples
Cellular location Membrane, Single-pass type I membrane protein

Documents

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Research Area

BMPR1B Rabbit pAb images

ABclonal:Immunohistochemistry - BMPR1B Rabbit pAb (A17295)}

Immunohistochemistry - BMPR1B Rabbit pAb (A17295)

Immunohistochemistry analysis of BMPR1B in paraffin-embedded human mammary cancer using BMPR1B Rabbit pAb (A17295) at dilution of 1:200 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
ABclonal:Immunohistochemistry - BMPR1B Rabbit pAb (A17295)}

Immunohistochemistry - BMPR1B Rabbit pAb (A17295)

Immunohistochemistry analysis of BMPR1B in paraffin-embedded human colon carcinoma using BMPR1B Rabbit pAb (A17295) at dilution of 1:200 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
ABclonal:Immunohistochemistry - BMPR1B Rabbit pAb (A17295)}

Immunohistochemistry - BMPR1B Rabbit pAb (A17295)

Immunohistochemistry analysis of BMPR1B in paraffin-embedded rat ovary using BMPR1B Rabbit pAb (A17295) at dilution of 1:200 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.

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Related Targets

Based on existing publications, the following genes are closely related to research on BMPR1B. (Numbers indicate number of published articles where both targets appear.)

1/

Related Research Area

Based on existing publications, the following research topics are related to BMPR1B. (Distance between topics and target gene indicate popularity.) BMPR1B

* Data provided by citexs.com, for reference only.

Publishing research using A17295? Please let us know so that we can cite the reference in this datasheet.

Antibodies (2)

Proteins (1)

Secondary Antibodies (23)

* For research use only. Not for therapeutic or diagnostic purposes.

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