Product Type > Antibodies > Primary Antibodies > Acetyl-specific Antibodies

Acetyl-DNMT1-K1127/K1129/K1131/K1133 Rabbit pAb (A5595)

Publication (1) Datasheet SDS

Tested applications:WBIHCIF/ICCIPChIPChIP-seqRIPFCFC(Intra)ELISAMeDIPNucleotide ArrayDBFACSCoIPReactivity:Human, Mouse, Rat

ABclonal:Immunofluorescence - Acetyl-DNMT1-K1127/K1129/K1131/K1133 Rabbit pAb (A5595)

Immunofluorescence analysis of C6 cells using Acetyl-DNMT1-K1127/K1129/K1131/K1133 antibody (A5595) at dilution of 1:100. Blue: DAPI for nuclear staining.

Overview

Product nameAcetyl-DNMT1-K1127/K1129/K1131/K1133 Rabbit pAb
Catalog No.A5595
Host speciesRabbit
Purification methodAffinity purification
IsotypeIgG

Background

This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants.

Immunogen information

ImmunogenA synthetic acetylated peptide around K1127 & K1129 & K1131 & K1133 of human DNMT1 (NP_001124295.1).
SequenceKGKGKGK
Gene ID1786
Swiss protP26358
SynonymsADCADN; AIM; CXXC9; DNMT; HSN1E; MCMT; m.HsaI; DNMT1
Calculated MW144kDa/183kDa/184kDa
Observed MWRefer to figures

Applications

ReactivityHuman, Mouse, Rat
Tested applicationsWBIHCIF/ICCIPChIPChIP-seqRIPFCFC(Intra)ELISAMeDIPNucleotide ArrayDBFACSCoIP
Recommended dilution
  • IHC 1:50 - 1:100
  • IF/ICC 1:50 - 1:100
Storage bufferStore at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3. May contain BSA. If BSA-free batch required, please contact us.
Application keyImmunohistochemistry    
Positive samples
Cellular locationNucleus
Customer validation

WB(Mus musculus)

Research Area

Acetyl-DNMT1-K1127/K1129/K1131/K1133 Rabbit pAb images

ABclonal:Immunofluorescence - Acetyl-DNMT1-K1127/K1129/K1131/K1133 Rabbit pAb (A5595)}

Immunofluorescence - Acetyl-DNMT1-K1127/K1129/K1131/K1133 Rabbit pAb (A5595)

Immunofluorescence analysis of C6 cells using Acetyl-DNMT1-K1127/K1129/K1131/K1133 antibody (A5595) at dilution of 1:100. Blue: DAPI for nuclear staining.

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Related Targets

Based on existing publications, the following genes are closely related to research on DNMT1. (Numbers indicate number of published articles where both targets appear.)

1/

Related Research Area

Based on existing publications, the following research topics are related to DNMT1. (Distance between topics and target gene indicate popularity.) DNMT1

* Data provided by citexs.com, for reference only.

Publishing research using A5595? Please let us know so that we can cite the reference in this datasheet.

Primary Antibodies (10)

Secondary Antibodies (26)

* For research use only. Not for therapeutic or diagnostic purposes.

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