Product Type > Antibodies > Primary Antibodies > Acetyl-specific Antibodies

Acetyl-DNMT1-K1127/K1129/K1131/K1133 Rabbit pAb (A5595)

Tested applications:WB IHC IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra)ELISA MeDIP Nucleotide Array DB FACS CoIPReactivity:Human, Mouse, Rat

Immunofluorescence analysis of C6 cells using Acetyl-DNMT1-K1127/K1129/K1131/K1133 antibody (A5595) at dilution of 1:100. Blue: DAPI for nuclear staining.

Overview

Product name	Acetyl-DNMT1-K1127/K1129/K1131/K1133 Rabbit pAb
Catalog No.	A5595
Host species	Rabbit
Purification method	Affinity purification
Isotype	IgG

This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants.

Immunogen information

Immunogen	A synthetic acetylated peptide around K1127 & K1129 & K1131 & K1133 of human DNMT1 (NP_001124295.1).
Sequence	KGKGKGK
Gene ID	1786
Swiss prot	P26358
Synonyms	ADCADN; AIM; CXXC9; DNMT; HSN1E; MCMT; m.HsaI; DNMT1
Calculated MW	144kDa/183kDa/184kDa
Observed MW	Refer to figures

Applications

Reactivity	Human, Mouse, Rat
Tested applications	WB IHC IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra)ELISA MeDIP Nucleotide Array DB FACS CoIP
Recommended dilution	IHC 1:50 - 1:100 IF/ICC 1:50 - 1:100
Storage buffer	Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3. May contain BSA. If BSA-free batch required, please contact us.
Application key	Immunohistochemistry
Positive samples
Cellular location	Nucleus
Customer validation	WB(Mus musculus)

Research Area

Acetyl-DNMT1-K1127/K1129/K1131/K1133 Rabbit pAb images

Immunofluorescence - Acetyl-DNMT1-K1127/K1129/K1131/K1133 Rabbit pAb (A5595)

Immunofluorescence analysis of C6 cells using Acetyl-DNMT1-K1127/K1129/K1131/K1133 antibody (A5595) at dilution of 1:100. Blue: DAPI for nuclear staining.

Product Protocols

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Related Targets

Based on existing publications, the following genes are closely related to research on DNMT1. (Numbers indicate number of published articles where both targets appear.)

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Related Research Area

Based on existing publications, the following research topics are related to DNMT1. (Distance between topics and target gene indicate popularity.) DNMT1

* Data provided by citexs.com, for reference only.