Product Type > Antibodies > Primary Antibodies > Other Modified Antibodies

2'-O-methyladenosine / Am Rabbit pAb (A2388)

Datasheet COA

Tested applications: WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra) ELISA MeDIP Nucleotide Array DB FACS CoIP FCM CUT&Tag meRIP Inhibition

Reactivity:Species independent

ABclonal:Dot Blot - 2'-O-methyladenosine / Am Rabbit pAb (A2388)

The 2'-O-methyladenosine / Am Rabbit pAb(A2388) are tested in Dot Blot against 2'-O-methyladenosine (Am), N6, 2'-O-dimethyladenosine(m6Am), adenosine(A) and N6-methyladenosine(m6A).

ABclonal:Dot Blot - 2'-O-methyladenosine / Am Rabbit pAb (A2388)

The 2'-O-methyladenosine / Am Rabbit pAb(4µg, A2388)are tested in Nucleotide Array against Am-1 Oligo, Am-2 Oligo and Am-4 Oligo(100nmol for each oligomer).
Am-1 Oligo:biotin-CTACGGCTAA(Am)CCTTGG
Am-2 Oligo:biotin-CUACGGCUAA(Am)CCUUGG
Am-4 Oligo:biotin-CTACGGCTAAACCTTGG.

You may also interested in:

Overview

Product name 2'-O-methyladenosine / Am Rabbit pAb
Catalog No. A2388
Host species Rabbit
Purification method Affinity purification
Isotype IgG

Background

Discovered in the 1970s, m6A is the most prevalent internal modification in polyadenylated mRNAs and long non-coding RNAs (lncRNAs) in higher eukaryotes. m6A is widely conserved among eukaryotic species that range from yeast, plants, flies to mammals, as well as among viral RNAs with a nuclear phase. The m6A-based modification is associated with a well-defined RNA motif, RRACH (R: A/G, H: A/C/U). As a representative of the epitranscriptome, m6A mRNA modifications participate in many vital activities in the cell, including stem cell self-renewal and differentiation, mRNA transcription, alternative splicing, nuclear export, translation, degradation, and microRNA processing. These processes determine the expression or inactivation of specific genes, which is vital for growth and development.(PMID: 30416848; PMID: 24662220; PMID: 30429466)

Immunogen information

Immunogen Chemical compounds corresponding to 2'-O-methyladenosine / Am.
Sequence Email for sequence
Gene ID
Swiss prot
Synonyms Am; 2'-O-methyladenosine; 2'-O-methyladenosine / Am
Calculated MW
Observed MW

Applications

Reactivity Species independent
Tested applications WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra) ELISA MeDIP Nucleotide Array DB FACS CoIP FCM CUT&Tag meRIP Inhibition
Recommended dilution
  • DB 1:500 - 1:2000
Storage buffer Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Application key
Positive samples
Cellular location

Documents

Certificate of Compliance

To download a Certificate of Compliance, please enter your Lot number below:

Lot number

2'-O-methyladenosine / Am Rabbit pAb images

ABclonal:Dot Blot - 2'-O-methyladenosine / Am Rabbit pAb (A2388)}

Dot Blot - 2'-O-methyladenosine / Am Rabbit pAb (A2388)

The 2'-O-methyladenosine / Am Rabbit pAb(A2388) are tested in Dot Blot against 2'-O-methyladenosine (Am), N6, 2'-O-dimethyladenosine(m6Am), adenosine(A) and N6-methyladenosine(m6A).
ABclonal:Dot Blot - 2'-O-methyladenosine / Am Rabbit pAb (A2388)}

Dot Blot - 2'-O-methyladenosine / Am Rabbit pAb (A2388)

The 2'-O-methyladenosine / Am Rabbit pAb(4µg, A2388)are tested in Nucleotide Array against Am-1 Oligo, Am-2 Oligo and Am-4 Oligo(100nmol for each oligomer).
Am-1 Oligo:biotin-CTACGGCTAA(Am)CCTTGG
Am-2 Oligo:biotin-CUACGGCUAA(Am)CCUUGG
Am-4 Oligo:biotin-CTACGGCTAAACCTTGG.

Inquire About This Product

Submit your question about A2388 below and we will get back to you within one business day.

Alternatively, call us at 888.754.5670.

Related Targets

Based on existing publications, the following genes are closely related to research on 2mA. (Numbers indicate number of published articles where both targets appear.)

1/

Related Research Area

Based on existing publications, the following research topics are related to 2mA. (Distance between topics and target gene indicate popularity.) 2mA

* Data provided by citexs.com, for reference only.

Publishing research using A2388? Please let us know so that we can cite the reference in this datasheet.

* For research use only. Not for therapeutic or diagnostic purposes.

Select size and quantity
Contact us to order