A reliable immunological method needs reliable antibodies and antibody services. ABclonal can provide custom antibody services that meet the demands of our customers around the world.
Polyclonal antibodies are a reliable and cost-efficient ...
Antibodies raised against these modifications have shown ...
The desired rabbit mAb is selected directly from B cells.
ABclonal also offer a number of optional services to ...
Proper design of a suitable antigen is the most critical step in getting a useful antibody.
Cross-examine the sequence provided by the customer with the information in multiple databases, such as NCBI.
Screen suitable, immunogenic protein or peptide candidates.
Compare BLAST searches with genome or protein databases to identify ideal protein or peptide candidates.
Perform protein alignments of homologs/orthologs/isoforms.
Refer to relevant publications to better understand the 3D structure of the protein and the protein-protein/protein-DNA interaction.
According to the customers’ demands and the target characteristics, our experts will choose the best way to get the best immunogen.
Each immunogen expressed by our protein R & D department was risen to the drug raw material level. We try to improve the protein expression level, protein solubility, protein purity by changing expression vectors and expressing host bacteria, multiple expression conditions, and various purification methods. Through renaturation and refolding, the immunogen was recovered crrect space epitopes, which improved the probability of antibody recognition of natural conformation proteins.
For the extremely poor specificity and difficult expression of the project, We choose the best region to synthesis peptide coupling KLH as antigen to immune animals through professional analysis.
High Throughput Screening
Antibody Service Flowchart