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Structural insights into preinitiation complex assembly on core promoters

Journal: Science

Publication Date: 4/1/2021

PubMed ID: 33795473

Referenced Products: TBP Rabbit pAb (A2192), POLR2B Rabbit pAb (A5928)

Sample Species: Homo sapien

Application: WB

Molecular basis of nucleosomal H3K36 methylation by NSD methyltransferases

Journal: Nature

Publication Date: 12/23/2020

PubMed ID: 33361816

Referenced Products: H3K36me1 Rabbit pAb (A2364)

Sample Species: Homo sapien

Application: WB

SPT5 stabilizes RNA polymerase II, orchestrates transcription cycles, and maintains the enhancer landscape

Journal: Molecular Cell

Publication Date: 9/10/2021

PubMed ID: 34534457

Referenced Products: Vinculin Rabbit mAb (A2752), H3K25ac1 Rabbit pAb (A7253), SUPT4H1 Rabbit pAb (A7933)

Sample Species: Homo sapien

Application: WB

Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis

Journal: Cancer Cell

Publication Date: 3/18/2021

PubMed ID: 33740421

Referenced Products: NRF2 Rabbit pAb (A11159)

Sample Species: Mus muculus

Application: WB

Targeting mitochondria-located circRNA SCAR alleviates NASH via reducing mROS output

Journal: Cell

Publication Date: 9/14/2020

PubMed ID: 32931733

Referenced Products: RNASEL Rabbit pAb (A9840)

Sample Species: Homo sapien

Application: WB

  • A Path To Effective Precision Therapeutics For Alzheimer’s Disease

    Before my grandmother passed, she had been battling severe dementia for a very long time, which made it difficult in many ways to have conversations with her. It would take several minutes for her to process who I was, and then it would seem like she would remember me and my family, but she would still have to ask for clarification several times even after we had answered her queries. I am grateful that she is in a better place now, but her challenges in the final years of her life deepened my empathy for people who suffer from dementia, and those who take care of them.

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  • ABclonal in Action: Autophagy as a Therapeutic Target

    Every now and then when I get hungry, I joke that my stomach is about to digest itself. For the longest time, human science was unaware that our cells could literally eat itself (or more precisely, parts of itself) as well! First described in the 1960s by Christian de Duve

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  • Traffic Management: The Indispensable Vesicular Transport System

    When I taught high school biology, a favorite part of the curriculum was cellular structures and functions. I set up an activity suggested by other experienced biology teachers that was based on the

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  • Plant Power: Plant Chemicals and Proteins for Human Health

    When I was growing up in Hong Kong, and even after I came to the United States, my parents and grandparents would periodically give me ginseng beverages and soups, which was not always pleasant due to the bitter taste.

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