Product Type > Proteins

Recombinant human Ubiquitin (K11 only) protein (RP10068)

Datasheet

Overview

Product name Recombinant human Ubiquitin (K11 only) protein
Catalog No. RP10068
Formulation Supplied in 20 mM Tris, 150 mM NaCl, 2 mM BME, 10% Glycerol.Contact us for customized product form or formulation.
Species Human
Ubiquitin (Ub) is a 76 amino acid protein widely expressed in the cytoplasmic and nucleus of cells. Ub is posttranslationally conjugated to proteins by the E1, E2, E3 protein ubiquitination cascade. Ub can be conjugated on proteins as monoUb or polyUb chains. Protein ubiquitination plays both proteolytic and nonproteolytic functions. Usually, polyubiquitinated proteins are targeted to the 26S proteasome for proteolysis. Typical concentration to support in vitro ubiquitination is 50-100 μM. In Ub(K11 only), all lysine residues but lysine 11 were substituted with arginines, thereby it only supports the formation of lysine 11-linked polyubiquitin chains.
Expressed Host E. coli
Tag 6×His tag
Storage This product is stable at ≤ -70°C for up to 6 months from the date of receipt.
For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature.

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* For research use only. Not for therapeutic or diagnostic purposes.

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