Product Type > Proteins

Recombinant Rat VEGF 164 Protein (RP01111)

Datasheet

Overview

Product name Recombinant Rat VEGF 164 Protein
Catalog No. RP01111
Description Recombinant Rat VEGF 164 Protein is produced by Yeast expression system. The target protein is expressed with sequence (Ala27-Arg190) of rat VEGF 164 (Accession #P16612-2) fused with no tags.
Purity > 95% by SDS-PAGE.
Endotoxin < 1.0 EU/μg of the protein by LAL method.
Formulation Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation.
Species Rat
This protein is a heparin-binding protein, which exists as a disulfide-linked homodimer. This growth factor induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis. Disruption of this gene in mice resulted in abnormal embryonic blood vessel formation. This gene is upregulated in many known tumors and its expression is correlated with tumor stage and progression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. There is also evidence for alternative translation initiation from upstream non-AUG (CUG) codons resulting in additional isoforms. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is antiangiogenic. Expression of some isoforms derived from the AUG start codon is regulated by a small upstream open reading frame, which is located within an internal ribosome entry site.
Synonym MVCD1; VAS; vascular endothelial growth factor A; Vasculotropin; VEGF; VEGFA; VEGF-A; VEGFMGC70609; VPF; VEGFA
Expressed Host P.Pichia
Tag No tag
Swiss-Prot P16612
Gene ID 83785
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
Reconstitution Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water.

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Proteins (1)

* For research use only. Not for therapeutic or diagnostic purposes.

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