Overview
Product name |
Recombinant Mouse EGF Protein |
Catalog No. |
RP00628 |
Description |
Recombinant Mouse EGF Protein is produced by E. coli expression system. The target protein is expressed with sequence (Asn977-Arg1029) of mouse EGF (Accession #P01132) fused with an initial Met at the N-terminus and a 6×His tag at the C-terminus. |
Purity |
> 95% by SDS-PAGE. |
Endotoxin |
< 1 EU/μg of the protein by LAL method. |
Formulation |
Lyophilized from a 0.2 μM filtered solution of PBS,pH 7.4Contact us for customized product form or formulation. |
Species |
Mouse |
Background
EGF is a single-pass type I membrane protein, containing 8 LDL-receptor class B repeats and 9 EGF-likedomains. EGF results in cellular proliferation, differentiation, and survival.EGF is a low-molecular-weightpolypeptide first purified from the mouse submandibular gland, but since then found in many human tissuesincluding submandibular gland, parotid gland. Salivary EGF, which seems also regulated by dietary inorganiciodine, also plays an important physiological role in the maintenance of oro-esophageal and gastric tissueintegrity. The biological effects of salivary EGF include healing of oral and gastroesophageal ulcers, inhibitionof gastric acid secretion, stimulation of DNA synthesis as well as mucosal protection from intraluminalinjurious factors such as gastric acid, bile acids, pepsin, and trypsin and to physical, chemical and bacterialagents.
Product information
Synonym |
beta-urogastrone; EGF; epidermal growth factor (beta-urogastrone); epidermal growth factor; HOMG4; pro-epidermal growth factor; URG; Urogastrone; EGF |
Expressed Host |
E. coli |
Tag |
C-6×His |
Swiss-Prot |
P01132 |
Gene ID |
13645 |
Usage guide
Storage |
Store the lyophilized protein at -20°C to -80 °C for long term. After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week. |
Reconstitution |
Reconstitute to a concentration of 0.1-0.5 mg/mL in 1X PBS. |
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* For research use only. Not for therapeutic or diagnostic
purposes.