Product Type > Proteins

Recombinant Human TNFRSF17/BCMA/CD269 Protein (RP02218)

Datasheet

Overview

Product name Recombinant Human TNFRSF17/BCMA/CD269 Protein
Catalog No. RP02218
Description Recombinant Human TNFRSF17/BCMA/CD269 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (BCMA(Met1-Ala54)&mFc(Pro99-Lys330)) of human TNFRSF17 (Accession #) fused with a Fc Tag at the C-terminal. .
Bio-Activity ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human BAFF, hFc tagged protein can bind Human BCMA, mFc tagged protein in a linear range of 0.03-15.625 ng/mL.
Purity > 95% by SDS-PAGE.
Formulation Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 42 % trehalose is added as protectants before lyophilization.
Species Human
B-cell maturation protein (BCMA or BCM), is also known as Tumor necrosis factor receptor superfamily member 17 (TNFRSF17), which is encoded by the TNFRSF17 gene. TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF). This receptor is expressed in immune organs and mature B cell lines. BCMA promotes B-cell survival and plays a role in the regulation of humoral immunity. BCMA can activate NF-kappa-B and JNK.
Synonym TNFRSF17; BCM; BCMA; CD269; TNFRSF13A
Expressed Host HEK293 cells
Tag C-mFc
Swiss-Prot Q02223
Gene ID 608
Storage Store the lyophilized protein at -20°C to -80°C for long term.
After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
Reconstitution Reconstitute with deionized water

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