Product Type > Proteins

Recombinant Human PD-1/PDCD1/CD279 Protein (RP02237)

Datasheet

Overview

Product name Recombinant Human PD-1/PDCD1/CD279 Protein
Catalog No. RP02237
Description Recombinant Human PD-1/PDCD1/CD279 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (PD-1(Phe24-Val170)&mFc(Pro99-Lys330)) of human PDCD1 (Accession #) fused with a Fc and His Tag at the C-terminal. .
Bio-Activity ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human PD1, mFc-His tagged protein can bind Anti-PD-1 Neutralizing antibody in a linear range of 0.24-6.49 ng/mL.
Purity > 95% by SDS-PAGE.
Formulation Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 32 % trehalose is added as protectants before lyophilization.
Species Human
This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.
Synonym PDCD1; CD279; PD-1; PD1; SLEB2; hPD-1; hPD-l; hSLE1; programmed cell death 1; PD-1; CD279; PD1; SLEB2; hPD-1; hPD-l; hSLE1; PD-1/CD279
Expressed Host HEK293 cells
Tag C-mFc&His
Swiss-Prot Q15116
Gene ID 5133
Storage Store the lyophilized protein at -20°C to -80°C for long term.
After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
Reconstitution Reconstitute with deionized water

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Antibodies (3)

Proteins (4)

* For research use only. Not for therapeutic or diagnostic purposes.

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