Product Type > Proteins

Recombinant Human Neurotrophin-3/NGF-2/NT-3 Protein (RP00496)

Publication (1) Datasheet

Overview

Product name Recombinant Human Neurotrophin-3/NGF-2/NT-3 Protein
Catalog No. RP00496
Description Recombinant Human Neurotrophin-3/NGF-2/NT-3 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Tyr139-Thr257) of human NT-3/Neurotrophin-3 (Accession #P20783).
Purity > 95% by SDS-PAGE.
Endotoxin < 1 EU/μg of the protein by LAL method.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 250mM NaCl, pH 7.2.Contact us for customized product form or formulation.
Species Human
Neurotrophin-3 (NT-3) is a member of the NGF family of neurotrophic factors and is structurally related to β -NGF, BDNF and NT-4. The NT3 cDNA encodes a 257 amino acid residue precursor protein with a signal peptideand a proprotein that are cleaved to yield the 119 amino acid residue mature NT3.The amino acid sequencesof mature human, murine and rat NT-3 are identical. NT-3 selectively promotes the differentiation and survivalof specific neuronal subpopulations in both the central as well as the peripheral nervous systems.
Synonym NTF3; HDNF; NGF-2; NGF2; NT-3; NT3
Expressed Host E. coli
Tag No tag
Swiss-Prot P20783
Gene ID 4908
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
Reconstitution Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

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