Product Type > Proteins

Recombinant Human IL-4 Protein (RP01597)

Datasheet

Overview

Product name Recombinant Human IL-4 Protein
Catalog No. RP01597
Description Recombinant Human IL-4 Protein is produced by Pichia expression system. The target protein is expressed with sequence (His25-Ser153) of human IL-4 (Accession #NP_000580.1) fused with and a 6×His tag at the N-terminus.
Bio-Activity Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 for this effect is 0.25-1.00 ng/mL.
Purity > 95% by SDS-PAGE.
Endotoxin <0.1EU/μg
Formulation Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
Species Human
Interleukin-4, also known as IL4, is a secreted protein that belongs to the IL-4 / IL-13 family. Interleukin-4 / IL4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation. It enhances both secretion and cell surface expression of IgE and IgG1. Interleukin-4 / IL4 also regulates the expression of the low-affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Interleukin-4 is essential for the switching of B cells to IgE antibody production and the maturation of T helper (Th) cells toward the Th2 phenotype.
Synonym BCGF-1; BCGF1; BSF-1; BSF1; IL-4; IL4; BCGF1; BSF-1; BSF1; IL-4
Expressed Host Pichia
Tag N-His
Swiss-Prot P05112
Gene ID 3565
Storage Store the lyophilized protein at -20°C to -80°C for 12 months.
After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
Reconstitution Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Inquire About This Product

Submit your question about RP01597 below and we will get back to you within one business day.

Alternatively, call us at 888.754.5670.

* For research use only. Not for therapeutic or diagnostic purposes.

Select size and quantity
Contact us to order