Product Type > Proteins

Recombinant Human IL-11 Protein (RP00474)

Datasheet

Overview

Product name Recombinant Human IL-11 Protein
Catalog No. RP00474
Description Recombinant Human IL-11 Protein is produced by P.Pichia expression system. The target protein is expressed with sequence (Gly23-Leu199) of human IL-11 (Accession #P20809).
Purity > 95% by SDS-PAGE.
Endotoxin < 1 EU/μg of the protein by LAL method.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 2% Glycine, pH 7.2.Contact us for customized product form or formulation.
Species Human
Interleukin 11 (IL-11) is a member of a family of human growth factors that includes human growth hormone, granulocyte colony-stimulating factor, and other growth factors. IL-11 is a thrombopoietic growth factor thatdirectly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells andinduces megakaryocyte maturation resulting in increased platelet production. It also promotes theproliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and eitherIL11RA1 or IL11RA2, It activates a signaling cascade that promotes cell proliferation. The signaling leads to theactivation of intracellular protein kinases and the phosphorylation of STAT3.
Synonym IL11; AGIF; IL-11
Expressed Host Yeast
Tag No tag
Swiss-Prot P20809
Gene ID 3589
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
Reconstitution Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water.

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* For research use only. Not for therapeutic or diagnostic purposes.

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