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Recombinant Human GITR Protein (RP01116)



Product nameRecombinant Human GITR Protein
Catalog No.RP01116
DescriptionRecombinant Human GITR Protein is produced by Mammalian expression system. The target protein is expressed with sequence (Gln26-Glu161) of human GITR (Accession #Q9Y5U5) fused with an Fc tag at the C-terminus.
Purity> 95% by SDS-PAGE.
Endotoxin< 1.0 EU/μg of the protein by LAL method.
FormulationLyophilized from a 0.22 μm filtered solution of PBS, pH7.4.Contact us for customized product form or formulation.
This protein is a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
SynonymTumor necrosis factor receptor superfamily member 18; TNFRSF18; Glucocorticoid-induced TNFRrelated protein; CD357; TNFRSF18; AITR; GITR
Expressed HostMammalian
Gene ID8784
StorageStore the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
ReconstitutionReconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water.

* For research use only. Not for therapeutic or diagnostic purposes.

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