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Recombinant Human GITR Protein (RP01116)

Datasheet

Overview

Product nameRecombinant Human GITR Protein
Catalog No.RP01116
DescriptionRecombinant Human GITR Protein is produced by Mammalian expression system. The target protein is expressed with sequence (Gln26-Glu161) of human GITR (Accession #Q9Y5U5) fused with an Fc tag at the C-terminus.
Purity> 95% by SDS-PAGE.
Endotoxin< 1.0 EU/μg of the protein by LAL method.
FormulationLyophilized from a 0.22 μm filtered solution of PBS, pH7.4.Contact us for customized product form or formulation.
SpeciesHuman
This protein is a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
SynonymTumor necrosis factor receptor superfamily member 18; TNFRSF18; Glucocorticoid-induced TNFRrelated protein; CD357; TNFRSF18; AITR; GITR
Expressed HostMammalian
TagC-Fc
Swiss-ProQ9Y5U5
Gene ID8784
StorageStore the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
ReconstitutionReconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water.

* For research use only. Not for therapeutic or diagnostic purposes.

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