Product Type > Proteins

Recombinant Human Alpha-synuclein/SNCA Protein (RP00610)

Datasheet

Overview

Product name Recombinant Human Alpha-synuclein/SNCA Protein
Catalog No. RP00610
Description Recombinant Human Alpha-synuclein/SNCA Protein is produced by E. coli expression system. The target protein is expressed with sequence (Met1-Ala140) of human SNCA/Alpha-synuclein (Accession #P37840).
Purity > 95% by SDS-PAGE.
Endotoxin < 1 EU/μg of the protein by LAL method.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.Contact us for customized product form or formulation.
Species Human
Alpha-Synuclein (SNCA) is a member of the Synuclein family. SNCA is expressed principally in brain but alsoexpressed in low concentrations in all tissues except liver. SNCA interacts with UCHL1, Phospholipase D andhistones. SNCA can include beta- and gamma-synuclein. In addition, SNCA is an important regulatorycomponent of vesicular transport in neuronal cells. It has been suggested that SNCA is related to thepathogenesis of Parkinson's Disease and neurodegenerative disorders. Defects in SNCA will lead to DementiaLewy Body (DLB).
Synonym PD1; NACP; PARK1; PARK4; SNCA
Expressed Host E. coli
Tag N-His
Swiss-Prot P37840
Gene ID 6622
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
Reconstitution Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water.

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