Product Type > Proteins

Recombinant Human Angiopoietin-like 3/ANGPTL3 Protein (RP01024)

Datasheet

Overview

Product name Recombinant Human Angiopoietin-like 3/ANGPTL3 Protein
Catalog No. RP01024
Description Recombinant Human Angiopoietin-like 3/ANGPTL3 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ser17-Pro220) of human ANGPTL3/Angiopoietin-like 3 (Accession #NP_055310.1) fused with a 6×His tag at the C-terminus.
Purity > 90% by SDS-PAGE.
Endotoxin < 0.1 EU/μg of the protein by LAL method.
Formulation Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation.
Species Human
Angiopoietin-like protein 3 (ANGPTL3) also known as Angiopoietin-related protein 3, Angiopoietin-5 (ANG-5) is a secreted glycoprotein that is structurally related to the angiopoietins.Human ANGPTL3 contains an N-terminal coiled coil domain and a C-terminal fibrinogen-like domain. The fibrinogen C-terminal domain is sufficient to mediate endothelial cell adhesion. ANGPTL3 is principally expressed in the liver and can exert activities related to both angiogenesis and lipid metabolism.ANGPTL3 directly inhibits lipoprotein lipase (LPL) and endothelial lipase (EL), enzymes responsible for hydrolyzing circulating triglycerides and HDL phospholipids.
Synonym ANG-5; ANGPT5; ANL3; FHBL2; ANGPTL3; ANGPT5; ANL3; FHBL2
Expressed Host HEK293 cells
Tag C-His
Swiss-Prot Q9Y5C1
Gene ID 27329
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
Reconstitution Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

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